APMAdvances in Precision Medicine2424-85922424-9106Bio-Byword Scientific Publishing Pty. Ltd.10.26689/APM.v11i8.16041ArticleAnalysis of Clinical Efficacy and Safety of Laparoscopic Repair in the Treatment of Gastroduodenal Perforationhttps://artdesignp.com/journal/APM/11/8/10.26689/APM.v11i8.16041KuangFuyuan20261182026-08-26Objective: To analyze the clinical efficacy and safety of laparoscopic repair in the treatment of gastroduodenal perforation. Methods: 96 patients with gastroduodenal perforation admitted to our hospital from March 2025 to March 2026 were selected and divided into 2 groups according to the surgical plan, with 48 patients in each group. The control group underwent traditional laparotomy perforation repair, and the observation group underwent laparoscopic perforation repair. The surgery-related indicators and complications were compared between the two groups. Results: The operation time of the observation group was slightly longer than that of the control group; however, the amount of intraoperative blood loss was significantly less; the time to get out of bed and hospital stay were shorter; and the postoperative complication rate was lower (p < 0.05). Conclusion: Laparoscopic repair has the characteristics of less trauma, faster postoperative recovery, and fewer complications when treating gastroduodenal perforation. The overall safety and therapeutic effect are better than traditional laparotomy. It is suitable for gradual promotion and use in primary hospitals. It will be more applicable to patients with a shorter onset time and acceptable basic physical conditions.Gastroduodenal perforation, laparoscopic repair, open repair, clinical efficacy, safety, postoperative complications

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