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<article xsi:noNamespaceSchemaLocation="http://jats.nlm.nih.gov/publishing/1.1/xsd/JATS-journalpublishing1-mathml3.xsd" dtd-version="1.1" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"><front><journal-meta><journal-id journal-id-type="publisher-id">IJGPN</journal-id><journal-title-group><journal-title>International Journal of General Practice Nursing</journal-title></journal-title-group><issn>2981-9415</issn><eissn>2981-9423</eissn><publisher><publisher-name>Bio-Byword Scientific Publishing Pty. Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.26689/IJGPN.v4i3.15240</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title>Exploration of the Multidimensional Effects of a New Sputum Drainage Strategy Using the Trendelenburg Position on Sputum Clearance Function in Children Undergoing Mechanical Ventilation</title><url>https://artdesignp.com/journal/IJGPN/4/3/10.26689/IJGPN.v4i3.15240</url><author>PanYangye,CaoJing,WeiJiayou,LingQiufen</author><pub-date pub-type="publication-year"><year>2026</year></pub-date><volume>4</volume><issue>3</issue><history><date date-type="pub"><published-time>2026-08-31</published-time></date></history><abstract>Objective: To investigate the multidimensional improvement effects of a new sputum drainage strategy combining a 30 degree Trendelenburg position, specialized position-changing pillows, and sedation intervention on sputum clearance function in pediatric patients undergoing mechanical ventilation. Methods: From January 2022 to December 2025, 95 children receiving mechanical ventilation were randomly divided into an observation group (48 cases) and a control group (47 cases). The observation group adopted a 30 degree Trendelenburg position, utilized specialized position-changing pillows, and received appropriate sedation, with drainage performed for approximately 2 hours per shift. The control group employed conventional sputum drainage methods. The effects of the new strategy were evaluated by comparing sputum volume, improvement in pulmonary rales, blood gas analysis indicators, and duration of mechanical ventilation between the two groups. Results: Sputum volumes on days 1, 3, and 5 in the observation group were (15.62&amp;plusmn;3.27) ml, (20.55&amp;plusmn;4.14) ml, and (22.38&amp;plusmn;4.55) ml, respectively, significantly higher than those in the control group, which were (10.24&amp;plusmn;2.82) ml, (15.36&amp;plusmn;3.52) ml, and (17.65&amp;plusmn;3.83) ml, respectively (all P&amp;lt;0.001). The overall improvement rate of pulmonary rales in the observation group was significantly higher than that in the control group (x2=7.251, P=0.007). On day 3 post-ventilation, PaO2 (85.67&amp;plusmn;6.25 mmHg) and OI (205.33&amp;plusmn;15.65 mmHg) in the observation group were significantly higher than those in the control group, while PaCO2 (38.53&amp;plusmn;3.87 mmHg) was significantly lower (all P&amp;lt;0.001). The duration of mechanical ventilation in the observation group was significantly shorter than that in the control group (t=4.850, P&amp;lt;0.001). Conclusion: The new sputum drainage strategy using the Trendelenburg position can significantly enhance sputum clearance efficiency, improve pulmonary ventilation and oxygenation status, and shorten the duration of mechanical ventilation in children through precise positional control and synergistic interventions, demonstrating significant clinical application value.</abstract><keywords>Pediatric mechanical ventilation, Trendelenburg position, Sputum drainage, Sputum clearance function</keywords></article-meta></front><body/><back><ref-list><ref id="B1" content-type="article"><label>1</label><element-citation publication-type="journal"><p>[1] Zhang Q, Zhang WT, Xie JX, et al., 2024, Application of the Best Evidence for Sedation Assessment in Critically Ill Children on Mechanical Ventilation. Journal of Nursing Science, 39(24): 1&amp;ndash;6.
[2] Cai WQ, Wang JN, Li M, et al., 2024, Evidence Summary for Early Pulmonary Rehabilitation in Children with Invasive Mechanical Ventilation. Chinese Journal of Nursing Management, 24(12): 1857&amp;ndash;1863.
[3] Zhang ZY, Liu JF, Ge M, et al., 2024, Evaluation of the Effects of Prone Position Ventilation in Children with Severe Pneumonia at High Altitudes. Chinese Journal of Nursing, 59(22): 2742&amp;ndash;2746.
[4] Wang HY, Tang JZ, Shang WY, et al., 2024, Analysis of Factors Influencing the Duration of Mechanical Ventilation After Congenital Heart Disease Surgery. Journal of Clinical Pediatrics, 42(7): 654&amp;ndash;658.
[5] Zhao Y, Yang XY, 2021, Effects of Sequential Enteral and Parenteral Nutrition Support on Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease Complicated by Respiratory Failure. Journal of Practical Clinical Medicine, 25(1): 41&amp;ndash;44.
[6] Li X, 2023, Analysis of the Effects of Critical Care Nursing on Patients with Acute Chronic Obstructive Pulmonary Disease Complicated by Respiratory Failure. Chinese Journal of Metallurgical Industry Medicine, 40(3): 289&amp;ndash;290.
[7] Yu SY, Zhang QY, Pan XY, et al., 2025, Research Progress on Bedside Point-of-care Ultrasound Assisting Nurses in Pulmonary Rehabilitation for Patients on Mechanical Ventilation. Journal of Nursing Management, 25(3): 220&amp;ndash;224.
[8] Lai SL, Guo SW, Lin JB, et al., 2024, Application of Prone Position Ventilation in Mechanically Ventilated Extremely Low Birth Weight Infants. Nursing Research, 38(20): 3755&amp;ndash;3757.
[9] Zhuang YN, Lin BQ, Chen YY, et al., 2024, Effects of Different Body Positions and Diaphragmatic Function Status on Mechanical Ventilation Outcomes in COPD Patients. Journal of Nursing Science, 39(3): 28&amp;ndash;30 + 44.
[10] Li MC, Chen XT, Qiu LX, 2023, Study on the Relationship Between Body Position and Central Venous Pressure in Critically Ill Children on Mechanical Ventilation. Nursing Research, 37(6): 975&amp;ndash;979.
[11] Chen J, Mao XR, Tang XH, et al., 2024, Evidence Summary for the Prevention and Nursing of Ocular Complications in Patients Undergoing Prone Position Mechanical Ventilation. Chinese Journal of Nursing Management, 24(12): 1874&amp;ndash;1879.
[12] Li F, Wang Y, Zhou Q, et al., 2023, Effects of Assisted Body Position Changes on Diaphragmatic Function after Weaning in Patients with Cerebral Infarction. Chinese Journal of Rehabilitation, 38(8): 465&amp;ndash;469.</p><pub-id pub-id-type="doi"/></element-citation></ref></ref-list></back></article>
