JCNRJournal of Clinical and Nursing Research2208-36852208-3693Bio-Byword Scientific Publishing Pty. Ltd.10.26689/JCNR.v10i8.15412ArticleDevelopment of an Evidence-Informed Early Oral Feeding Intervention Protocol for Patients Undergoing Colorectal Cancer Surgery: A Delphi Consensus Studyhttps://artdesignp.com/journal/JCNR/10/8/10.26689/JCNR.v10i8.15412JiangYuzhen,XuYan,XuJiexuan,PengLifen,PengJianjun,ZhangSangu,ChenMeiquan,ChenYuying20261082026-08-31This study aimed to develop an evidence-informed early oral feeding (EOF) intervention protocol for patients undergoing colorectal cancer surgery. Based on a previously completed evidence synthesis, an initial protocol was developed and refined through a two-round Delphi survey involving experts in gastrointestinal surgery and nutrition. Seventeen experts were invited, and 15 completed both rounds, with response rates of 88% and 100%, respectively. The coefficients of expert authority were 0.95 and 0.94, and Kendall’s W coefficients were 0.114 and 0.218, respectively (p = 0.002 and p < 0.001). After two rounds of consultation, a protocol comprising 6 first-level and 37 second-level items was developed, covering nutritional risk screening and assessment, nutritional therapy, energy and protein management, staged oral feeding, and postoperative feeding tolerance assessment and management. The protocol provides a structured, evidence-informed approach to EOF implementation and may facilitate its standardized clinical application.Colorectal cancer, Early oral feeding, Perioperative nursing, Protocol development, Delphi method

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