BASBone and Arthrosurgery Science3083-48562981-8222Bio-Byword Scientific Publishing Pty. Ltd.10.26689/bas.v1i3.5828ArticleEvaluation of Platelet-Rich Plasma Combined with Minimally Invasive Arthroscopic Surgery for the Treatment of Degenerative Knee Jointshttps://artdesignp.com/journal/BAS/1/3/10.26689/bas.v1i3.5828XiaoXinglei,LiuShanglun,ChenGuoqing,CaoChen2023132023-12-26Objective: To evaluate the effect of platelet-rich plasma and arthroscopic minimally invasive surgery treatment in patients with degenerative knee joint lesions. Methods: From July 2015 to July 2022, 80 patients with degenerative knee joint lesions were selected and randomly divided into two groups. Group A received platelet-rich plasma and minimally invasive arthroscopic surgery treatment while group B received only minimally invasive arthroscopic surgery treatment. The treatment efficacy, visual analog scores (VAS), knee osteoarthritis severity index (ISOA), knee function scores (KSS), and Lysholm knee scores were compared. Results: The treatment efficacy in group A was higher than that in group B (P < 0.05); at 3 and 6 months after surgery, the VAS and ISOA scores of group A were lower than those of group B (P < 0.05), while the KSS and Lysholm scores of group A were higher than those of group B (P < 0.05); the treatment satisfaction in group A was higher than that in group B (P < 0.05). Conclusion: Patients with knee joint degeneration receiving platelet-rich plasma and minimally invasive arthroscopic surgery treatment can restore knee joint function and reduce local pain,which is efficient and feasible for clinical application.

Xie H, Wang B, Fu W, et al., 2020, Evaluation of the Effect of Using Platelet-Rich Plasma Combined with Sodium Citrate in the Treatment of Osteoarthritis of the Knee Joint During Arthroscopy. Chinese Journal of Clinicians, 48(3): 325–328.

Gu W, 2022, Study on the Effect of Arthroscopic Cleanup Combined with Platelet-Rich Plasma in the Treatment of Moderate-To-Severe Osteoarthritis of the Knee. Journal of Hebei Medical University, 43(4): 402–406, 411.

He X, Chen H, Liu J, et al., 2021, Meta-Analysis of Platelet-Rich Plasma Combined with Microfracture VersusMicrofracture in the Treatment of Knee Cartilage Lesions. Chinese Tissue Engineering Research, 25(6): 964–969.

Liu Z, Shen Y, Dai B, et al., 2021, Short-Term Efficacy of High Open Tibial Osteotomy and Microfracture Combined with Platelet-Rich Plasma Implantation in the Treatment of Osteoarthritis of the Medial Compartment of the Knee. Chinese Journal of Bone and Joint Surgery, 14(12): 990–994.

Wei H, Zhao Z, 2021, Analysis of the Effect of Arthroscopic Cleaning Combined with Joint Cavity Drugs in the Treatment of Osteoarthritis of Knee Joint. China Modern Drug Application, 15(13): 148–151.

Li X, Qin H, Tan H, 2020, Arthroscopic Cleaning of Proximal Fibular Osteotomy Combined with Platelet-Rich Plasma in the Treatment of Osteoarthritis of the Knee Joint. Chinese Journal of Bone and Joint Injury, 35(12): 1299–1301.

Lu Q, Li L, Zhou Z, et al., 2021, Analysis of the Efficacy of Arthroscopic Cleaning Combined with Platelet-Rich Plasma Injection in the Treatment of Osteoarthritis of the Knee Joint. Laboratory Medicine and Clinics, 18(13): 1915–1918.

Ma X, Li P, Wu L, 2023, Clinical Efficacy Analysis of Arthroscopic Microfracture Combined with Platelet-Rich Plasma in the Treatment of Osteoarthritis of the Knee Joint. Chinese and Foreign Medical Treatment, 42(9): 49–53.

Wan S, Liu J, 2021, A Prospective Study on the Clinical Effect of Autologous Platelet-Rich Plasma Transplantation in the Treatment of Knee Osteoarthritis. Chinese Journal of Health and Nutrition, 31(13): 59–60.

Liu Y, Xiao J, Chen L, et al., 2022, Comparative Analysis of Clinical Efficacy of Intra-Articular Injection of Sodium Hyaluronate and Platelet-Rich Plasma in the Treatment of Osteoarthritis of the Knee Joint. Modern Diagnosis and Treatment, 33(6): 795–798.