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<article xsi:noNamespaceSchemaLocation="http://jats.nlm.nih.gov/publishing/1.1/xsd/JATS-journalpublishing1-mathml3.xsd" dtd-version="1.1" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"><front><journal-meta><journal-id journal-id-type="publisher-id">BAS</journal-id><journal-title-group><journal-title>Bone and Arthrosurgery Science</journal-title></journal-title-group><issn>3083-4856</issn><eissn>2981-8222</eissn><publisher><publisher-name>Bio-Byword Scientific Publishing Pty. Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.26689/bas.v3i6.13319</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title>The Impact of Preemptive Analgesia Combined with Multimodal Analgesia on Perioperative Pain and Postoperative Fracture Healing in Elderly Patients with Hip Fractures</title><url>https://artdesignp.com/journal/BAS/3/6/10.26689/bas.v3i6.13319</url><author>WangHaihang</author><pub-date pub-type="publication-year"><year>2025</year></pub-date><volume>3</volume><issue>6</issue><history><date date-type="pub"><published-time>2025-12-31</published-time></date></history><abstract>Objective: To investigate the impact of preemptive analgesia combined with multimodal analgesia on perioperative pain and postoperative fracture healing in elderly patients with hip fractures. Methods: A total of 202 patients who underwent total hip arthroplasty from January 2024 to December 2024 were selected and divided into two groups based on different analgesic methods: a control group receiving routine postoperative multimodal analgesia and a study group receiving preemptive analgesia combined with multimodal analgesia, each with 101 cases. The analgesic effects were compared between the two groups. Results: The pain scores of the study group at all postoperative time points were significantly lower than those of the control group (P &amp;lt; 0.05); the number of patient-controlled intravenous analgesia pumps and the frequency of rescue analgesia in the study group were significantly lower than those in the control group (P &amp;lt; 0.05); the levels of stress response indicators in the study group were significantly lower than those in the control group after surgery (P &amp;lt; 0.05); the fracture healing time in the study group was significantly shorter than that in the control group (P &amp;lt; 0.05). Conclusion: The application of preemptive analgesia combined with multimodal analgesia in elderly patients with hip fractures can provide superior perioperative analgesic effects, effectively reduce surgical stress responses, promote early functional rehabilitation, and have a positive effect on postoperative fracture healing.</abstract><keywords/></article-meta></front><body/><back><ref-list><ref id="B1" content-type="article"><label>1</label><element-citation publication-type="journal"><p>Wang H, Lu H, Zhou D, et al., 2023, Effects of Preoperative Fascia Iliaca Compartment Block on Perioperative Analgesia and Sleep Quality in Elderly Patients with Hip Fractures. Chongqing Medicine, 52(22): 3465–3469.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B2" content-type="article"><label>2</label><element-citation publication-type="journal"><p>Wang P, Shi R, 2025, Observation on the Application Effect of Ropivacaine Combined with Dexmedetomidine and Dexamethasone for Fascia Iliaca Compartment Block in Postoperative Analgesia of Elderly Patients with Hip Fractures. Shandong Medical Journal, 65(08): 72–75.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B3" content-type="article"><label>3</label><element-citation publication-type="journal"><p>Li C, Ge W, Yang K, et al., 2023, Study on the Use of Ultrasound-Guided Continuous Fascia Iliaca Compartment Block for Perioperative Analgesia in Elderly Patients with Hip Fractures. China Journal of Orthopaedics and Traumatology, 36(11): 1046–1051.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B4" content-type="article"><label>4</label><element-citation publication-type="journal"><p>Liu P, Han Y, Gong J, et al., 2024, Comparison of Early Analgesic Effects of Iliopsoas Plane Block and Fascia Iliaca Compartment Block Above the Inguinal Ligament in Patients with Hip Fractures. International Journal of Anesthesiology and Resuscitation, (4): 366–371.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B5" content-type="article"><label>5</label><element-citation publication-type="journal"><p>Yang S, Cai J, Zang Q, et al., 2023, Effect of Ultrasound-Guided FICB Combined with Dexmedetomidine for Analgesia Before Positioning in Elderly Patients with Hip Fractures. Clinical Misdiagnosis &amp; Mistreatment, 36(04): 126–130.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B6" content-type="article"><label>6</label><element-citation publication-type="journal"><p>Zhong H, Wang X, Qin Q, et al., 2024, Analgesic Effect of Fascia Iliaca Compartment Block Above the Inguinal Ligament in Patients with Hip Fractures. Chinese Journal of Anesthesiology, 44(12): 1450–1455.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B7" content-type="article"><label>7</label><element-citation publication-type="journal"><p>Gao X, Sheng L, Ma Y, 2025, Application Effect of Ultrasound-Guided Fascia Iliaca Compartment Block Combined with Flurbiprofen Axetil Preemptive Analgesia in Elderly Patients Undergoing Hip Arthroplasty. Journal of Xinxiang Medical University, 42(09): 744–748 + 754.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B8" content-type="article"><label>8</label><element-citation publication-type="journal"><p>Ding P, Zhang Q, Wang H, et al., 2024, Effects of Dexmedetomidine Combined with Ultrasound-Guided Nerve Block on Postoperative Analgesia, Immune Stress, and Pain Mediators in Patients with Hip Fractures Complicated by Diabetes Mellitus. Progress in Modern Biomedicine, 24(16): 3176–3180.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B9" content-type="article"><label>9</label><element-citation publication-type="journal"><p>Han Y, Jiang P, Wu J, 2023, Meta-Analysis of the Effect of Preventive Nerve Block Analgesia on Perioperative Analgesia in Patients with Hip Fractures. Journal of Clinical Anesthesiology, 39(10): 1071–1077.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B10" content-type="article"><label>10</label><element-citation publication-type="journal"><p>Wu L, Zeng S, Zhong L, 2025, Analysis of Inflammatory Factor Changes and Risk Factors for Poor Early Postoperative Prognosis in Elderly Patients Undergoing Hip Surgery. Hainan Medical Journal, 36(4): 488–492.</p><pub-id pub-id-type="doi"/></element-citation></ref></ref-list></back></article>
