CNRClinical Neuroscience Research3083-48992981-8133Bio-Byword Scientific Publishing Pty. Ltd.10.26689/cnr.v2i4.9197ArticleResearch Progress on the Correlation between Oral Diseases and Chronic Kidney Diseaseshttps://artdesignp.com/journal/CNR/2/4/10.26689/cnr.v2i4.9197ShaoYuhan2024242024-12-26Objective: To review the research progress on the correlation between oral diseases and chronic kidney diseases. Methods: Recent Chinese literature on the treatment, analysis, and correlation studies of oral diseases and chronic kidney diseases was collected. A comprehensive review, analysis, induction, and organization of the literature were conducted. Results: A high correlation exists between oral diseases and chronic kidney diseases, which mutually reinforce each other. Conclusion: A deep-level association exists between oral diseases and chronic kidney diseases. Persistent inflammatory symptoms can promote the elevation of C-reactive protein, interleukin-6, and tumor necrosis factor-alpha, thereby exacerbating the development of chronic kidney diseases. Therefore, clinicians should comprehend the mechanism of interaction between oral diseases and chronic kidney diseases to foster diverse clinical thinking, improve the treatment efficacy of chronic kidney diseases, and effectively shorten disease duration.

Wang Y, 2023, Clinical Investigation and Correlation Analysis of Oral Disease Status in Patients Undergoing Maintenance Hemodialysis, dissertation, Jiangsu University.

Guo S, 2021, Characteristics of Oral Microbiota in Patients with Chronic Kidney Disease and Its Non-Invasive Diagnostic Value, dissertation, Zhengzhou University.

Yuan Q, 2021, Oral Implant Treatment for Patients with Chronic Kidney Disease. Journal of Prevention and Treatment for Stomatological Diseases, 29(3): 145–150.

Lai J, Bai Y, Bai Y, et al., 2020, Meta-Analysis of the Effect of Periodontal Basic Therapy on Inflammatory Factors in Patients with Chronic Kidney Disease and Periodontitis. West China Journal of Stomatology, 38(6): 672–680.

Guo F, 2021, The Role of Nuclear Factor-Kappa B Inflammatory Pathway in Periodontitis-Induced Chronic Kidney Disease, dissertation, Xinjiang Medical University.

Guo F, Sang X, Chahan S, et al., 2020, The Role of Nuclear Factor-Kappa B Pathway in Periodontitis-Induced Chronic Kidney Disease. Chinese Journal of Practical Diagnosis and Therapy, 34(9): 869–873.

Bi C, 2020, The Effect of Periodontitis on Renal Structure and Expression of Related Factors in Mice with Renal Interstitial Fibrosis, dissertation, Anhui Medical University.

Gao L, Guo J, 2014, The Effect of Non-Surgical Periodontal Therapy on Periodontal Status and Serum C-Reactive Protein Levels in Patients with Chronic Kidney Disease and Periodontitis. Journal of Oral Science Research, 30(5): 470–472.

Wang Y, Hu W, Fang S, et al., 2019, The Influence and Possible Mechanism of Suspected Pathogenic Bacteria of Periodontitis on Chronic Kidney Disease. Chinese Journal of Practical Stomatology, 12(9): 573–576.

Wu H, Ye W, Lu H, 2019, Research Progress on the Interaction and Mechanism between Periodontitis and Chronic Kidney Disease. Chinese Journal of Oral Medical Research (Electronic Edition), 13(2): 119–123.

Zeng Q, 2021, Study on the Differences in Oral Flora Composition of Hemodialysis Patients with Chronic Kidney Disease Stage 5, dissertation, Fujian Medical University.

Yu W, Wang C, Tang G, 2017, The Role of Periodontitis and Psoriasis in the Development of Chronic Kidney Disease. Journal of Clinical Stomatology, 33(1): 59–62.

Zhang D, Dou J, Shi L, et al., 2019, Study on the Mutual Promotion Mechanism of Periodontitis and Chronic Kidney Disease in Elderly Patients. Electronic Journal of General Stomatology, 6(10): 22–24.

Yu Y, Li Q, Liu Z, et al., 2023, A Case of Tooth Extraction in a Patient with Multiple Systemic Diseases Caused by Chronic Kidney Disease. Journal of Oral Science Research, 39(7): 652–653.

Ma Y, Yang X, 2023, Apical Periodontitis Aggravates Chronic Kidney Disease: High-Throughput Sequencing and Immunological Analysis. Compilation of Papers from the 16th National Conference on Cariology and Endodontics, 2023: 4.