CRCardiovascular Reviews3083-48802981-8109Bio-Byword Scientific Publishing Pty. Ltd.10.26689/cr.v1i2.5294ArticleEfficacy and Safety of Percutaneous Closure in Patients with Patent Foramen Ovale and Migrainehttps://artdesignp.com/journal/CR/1/2/10.26689/cr.v1i2.5294YanGuanghua,XueYibai,XingZheng2023122023-09-25Objective: To analyze the therapeutic effect of percutaneous closure of patent foramen ovale (PFO) and migraine. Methods: A total of 150 patients with PFO and migraine who were admitted to the hospital from January 2021 to May 2023 were recruited and divided into groups by random number table, the study group took percutaneous closure and drug treatment, and the control group took conventional drug treatment. The treatment effects between the groups were compared. Results: The total effective rate of the study group was higher than that of the control group (P < 0.05). Before treatment, there was no difference in migraine quantitative evaluation indicators between the groups (P > 0.05). After treatment, the migraine quantitative evaluation indicators in the study group were better than those in the control group (P < 0.05). The complication rate of the study group was lower than that of the control group (P < 0.05). Followed up for 1 to 3 months, the recurrence rate of the study group was lower than that of the control group (P < 0.05). Conclusion: Percutaneous closure for patients with PFO and migraine can improve the symptoms of migraine, enhance the curative effect, and have fewer postoperative complications.

Xiao J, Wang Q, Geng J, et al., 2019, Safety and Effectiveness Analysis of Transcatheter Closure of Patent Foramen Ovale in the Treatment of Migraine. Chinese Journal of Interventional Cardiology, 27(6): 303–308.

Pang Z, Li S, Zhao H, et al., 2019, Correlation Analysis between Headache Attacks and 5-Hydroxytryptamine Before and After Interventional Closure in Patients with Migraine Complicated with Patent Foramen Ovale. Journal of Cardiovascular and Cerebrovascular Diseases of Integrated Traditional Chinese and Western Medicine, 17(11): 1735–1738.

Hu J, Tan L, Wang J, 2022, Observation of Clinical Efficacy after Interventional Closure in Patients with Unclosed Foramen Ovale and Migraine. Guangdong Medicine, 43(8): 1041–1046.

Chu Y, Zhang Y, Luo J, et al., 2019, Analysis of Mid-Term Follow-Up Effect of Percutaneous Foramen Ovale Closure in Preventing Recurrent Neurological Events. Journal of Cardiovascular and Cerebrovascular Diseases of Integrated Traditional Chinese and Western Medicine, 17(11): 1747–1750.

Xu J, Jiang G, Liu T, et al., 2021, Clinical Experience of Interventional Closure of Atrial Septal Defect or Unclosed Foramen Ovale with Atrial Septal Tumor. Chinese Journal of Interventional Cardiology, 29(6): 324–328.

Wang Y, Qiu E, Wang G, et al., 2019, The Relationship between Patent Foramen Ovale and Migraine and the Clinical Efficacy After Closure. Chinese Journal of Pain Medicine, 25(5): 344–350.

Dou Q, Yu X, Qian C, et al., 2022, Effect of Residual Shunt on Migraine with Aura After Closure of Patent Foramen Ovale. China Cardiovascular Journal, 27(4): 337–341.

Du Y, Zhang H, Xin K, et al., 2019, Clinical Efficacy of Closure Surgery in Patients with Unclosed Foramen Ovale and Migraine. Journal of Practical Medicine, 35(5): 776–778 + 782.

Li X, Guo Y, Liang F, et al., 2020, Analysis of Short- and Mid-Term Curative Effect of Interventional Closure in the Treatment of Unclosed Foramen Ovale and Migraine. Journal of Cardiovascular and Cerebrovascular Diseases of Integrated Traditional Chinese and Western Medicine, 18(1): 170–172.

Wuyun QM, Wang Y, Ma F, et al., 2022, Analysis of Curative Effect and Influencing Factors of Interventional Closure in Patients with Migraine Complicated with Patent Foramen Ovale. Journal of Clinical Surgery, 30(8): 758–761.

Sun Z, Zhang G, Zhang H, et al., 2020, Observation and Analysis of Platelet-Related Indicators and Headache Relief in 111 Patients with Patent Foramen Ovale and Migraine after Interventional Closure. Chinese Journal of Interventional Cardiology, 28(10): 571–574.

Cheng Z, Qiu Q, Li Y, et al., 2021, Clinical Efficacy and Safety of Interventional Closure in Patients with Migraine Complicated with Patent Foramen Ovale. Lingnan Cardiovascular Disease Journal, 27(5): 558–562.

Hang Y, Tang Y, Li B, et al., 2020, The Effect and Recent Follow-Up Observation of Transcatheter Occlusion in the Treatment of Migraine with Unclosed Foramen Ovale. Chinese Cardiovascular Disease Research, 18(9): 814–818.

Lei M, Li Q, Xu K, et al., 2019, Observational Study on Closure Therapy of Patients with Migraine Complicated with Patent Foramen Ovale. Journal of Clinical Internal Medicine, 36(9): 636–637.

Ma J, Liao H, Li L, et al., 2023, Clinical Characteristics of Migraine Patients with Patent Foramen Ovale and Intervention Effect of Transcatheter Closure of Patent Foramen Ovale. Hebei Medicine, 45(2): 228–230 + 234.