CRCardiovascular Reviews3083-48802981-8109Bio-Byword Scientific Publishing Pty. Ltd.10.26689/cr.v1i3.5746ArticleResearch Progress on Dexmedetomidine Regulating Autophagy in the Treatment of Acute Lung Injuryhttps://artdesignp.com/journal/CR/1/3/10.26689/cr.v1i3.5746LiGuanrong,LiMin,WangYing,MaHuijie,ZhangBoya,ChenJun,SunYingui2023132023-12-28Dexmedetomidine, extensively utilized as an intravenous anesthetic in anesthesia, intensive care units, and other related medical departments, exhibits significant anti-inflammatory effects while inducing sedation. Numerous studies have demonstrated its capability to regulate autophagy, thereby exerting potent anti-inflammatory effects and offering therapeutic benefits in the treatment of acute lung injury. This article comprehensively reviews the mechanisms underlying autophagy, the role of dexmedetomidine in autophagy regulation, and the protective effects it conders in the context of acute lung injury. By doing so, it contributes positively to the arsenal of strategies aimed at both preventing and treating acute lung injury.

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