<?xml version="1.1" encoding="utf-8"?>
<article xsi:noNamespaceSchemaLocation="http://jats.nlm.nih.gov/publishing/1.1/xsd/JATS-journalpublishing1-mathml3.xsd" dtd-version="1.1" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"><front><journal-meta><journal-id journal-id-type="publisher-id">CR</journal-id><journal-title-group><journal-title>Cardiovascular Reviews</journal-title></journal-title-group><issn>3083-4880</issn><eissn>2981-8109</eissn><publisher><publisher-name>Bio-Byword Scientific Publishing Pty. Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.26689/cr.v2i4.9359</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title>Antiphospholipid Syndrome Misdiagnosed as Infective Endocarditis: A Case Report</title><url>https://artdesignp.com/journal/CR/2/4/10.26689/cr.v2i4.9359</url><author>LiYang,WuYizhen,YangGuang</author><pub-date pub-type="publication-year"><year>2025</year></pub-date><volume>2</volume><issue>4</issue><history><date date-type="pub"><published-time>2025-01-13</published-time></date></history><abstract>This article presents a retrospective study of a case that was initially misdiagnosed as infective endocarditis but was later diagnosed as antiphospholipid syndrome (APS) upon further evaluation. The study aims to explore the clinical manifestations of APS and increase clinicians’ awareness of its non-specific manifestations. The ultimate goal is to provide effective treatment as early as possible and prolong patients’ survival.</abstract><keywords/></article-meta></front><body/><back><ref-list><ref id="B1" content-type="article"><label>1</label><element-citation publication-type="journal"><p>Mezhov V, Segan JD, Tran H, et al., 2019, Antiphospholipid Syndrome: A Clinical Review. Medical Journal of Australia, 211(4): 1–5.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B2" content-type="article"><label>2</label><element-citation publication-type="journal"><p>Rodriguez-Pinto I, Espinosa G, Cervera R, 2020, Precision Medicine and the Antiphospholipid Syndrome: What Is the Future? Clinical Rheumatology, 39(4): 1015–1017.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B3" content-type="article"><label>3</label><element-citation publication-type="journal"><p>Durcan L, Petri M, 2019, Clinical Aspects of Antiphospholipid Syndrome. Dubois’ Lupus Erythematosus and Related Syndromes (Ninth Edition), Elsevier, Amsterdam, 532–542.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B4" content-type="article"><label>4</label><element-citation publication-type="journal"><p>Kato T, Takama N, Harada T, et al., 2020, Nonbacterial Thrombotic Endocarditis – A Rare Case of Acute Libman-Sacks Endocarditis Complicated by Multiple Cerebral Infarcts: Case Report and Literature Review. CASE (Phila), 4(6): 507–511.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B5" content-type="article"><label>5</label><element-citation publication-type="journal"><p>Chinese Medical Association Perinatal Medicine Branch, 2020, Expert Consensus on Diagnosis and Management of Obstetric Antiphospholipid Syndrome. Chinese Journal of Perinatal Medicine, 23(8): 517–522.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B6" content-type="article"><label>6</label><element-citation publication-type="journal"><p>Zhang J, Zhou B, 2011, Progress in Pathogenesis, Diagnosis, and Treatment of Antiphospholipid Antibody. Journal of Clinical Practice Hospital, 8(2): 45–48.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B7" content-type="article"><label>7</label><element-citation publication-type="journal"><p>Huang Y, Chen X, Wang X, et al., 2020, Diagnosis of Libman-Sacks Endocarditis by Echocardiography: A Case Report. Chinese Journal of Clinical Imaging, 31(1): 72.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B8" content-type="article"><label>8</label><element-citation publication-type="journal"><p>Zhao JL, Shen HL, Chai KX, et al., 2020, Diagnosis and Treatment of Antiphospholipid Syndrome. Chinese Journal of Internal Medicine, 61(9): 1000–1007.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B9" content-type="article"><label>9</label><element-citation publication-type="journal"><p>National Rheumatology Data Center, Chinese Medical Doctor Association, Rheumatology and Immunology Physicians Branch, Autoantibody Detection Professional Committee, National Clinical Medical Research Center for Immune Diseases, 2019, Expert Consensus on Clinical Application of Antiphospholipid Antibody Detection. Chinese Journal of Internal Medicine, 58(7): 496–500.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B10" content-type="article"><label>10</label><element-citation publication-type="journal"><p>Arslan E, Branch DW, 2020, Antiphospholipid Syndrome: Diagnosis and Management in the Obstetric Patient. Best Practice &amp; Research Clinical Obstetrics and Gynaecology, 2020(64): 31–40.</p><pub-id pub-id-type="doi"/></element-citation></ref></ref-list></back></article>
