JCNRJournal of Clinical and Nursing Research2208-36852208-3693Bio-Byword Scientific Publishing Pty. Ltd.10.26689/jcnr.v10i6.15534ArticleFlow Rate Control and Optimization of RCA Infusion System Based on ADRC and Two-Stage Calcium Supplementation Modelhttps://artdesignp.com/journal/JCNR/10/6/10.26689/jcnr.v10i6.15534XuChao,DingDamin,WangChaobin20261062026-06-30Based on the established two-stage mathematical model of Regional Citrate Anticoagulation (RCA), an automated RCA infusion system is constructed. Aiming at the flow rate accuracy problem of peristaltic pumps under variable pressure environments, a flow rate control algorithm based on Active Disturbance Rejection Control (ADRC) is designed, combined with pressure compensation and surface calibration methods. The experimental results show that this method can achieve high-precision infusion under different pressure differences and meet clinical requirements.

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