JCNRJournal of Clinical and Nursing Research2208-36852208-3693Bio-Byword Scientific Publishing Pty. Ltd.10.26689/jcnr.v10i6.15548ArticleMultimodal Treatment for Chronic Thromboembolic Pulmonary Hypertension: A Case Reporthttps://artdesignp.com/journal/JCNR/10/6/10.26689/jcnr.v10i6.15548TangYinjiang,XuOu,ZhangChunmei20261062026-06-30Chronic thromboembolic pulmonary hypertension (CTEPH) is a severe disease characterized by pulmonary thromboembolism and vascular remodeling, the pathogenesis of which has not been fully elucidated. Currently, it is believed that the disease primarily originates from the shedding of thromboemboli from the right heart system, leading to mechanical obstruction of the pulmonary artery, which in turn triggers local inflammatory reactions, endothelial damage, and vascular remodeling. This results in elevated pulmonary artery pressure, ultimately leading to right heart failure. In recent years, a multimodal treatment strategy combining balloon pulmonary angioplasty (BPA) with targeted pharmacotherapy has demonstrated significant efficacy in the treatment of CTEPH. This article reports the diagnosis and treatment process of a 68-year-old female patient with CTEPH. After undergoing BPA combined with soluble guanylyl cyclase stimulators (riociguat), the patient’s clinical symptoms and hemodynamic parameters significantly improved.

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