JCNRJournal of Clinical and Nursing Research2208-36852208-3693Bio-Byword Scientific Publishing Pty. Ltd.10.26689/jcnr.v1i2.122Articlehttps://artdesignp.com/journal/JCNR/1/2/10.26689/jcnr.v1i2.122Hua ShuangChen2021122021-07-30Objective: To analyse and discuss the related aspects of the nursing effect of comprehensive nursing intervention in elderly patients with severe pneumonia. Methods: 150 cases of senile severe pneumonia were randomly divided into observation group and control group. 75 patients were distributed to each control group and observation group, the control group was applied with conventional nursing intervention, observation group was applied with comprehensive nursing intervention, the two groups of clinical efficacy and quality of life and related care satisfaction were compared. Results: The effective rate of treatment was 90.67% (68/75) in the observation group, which was significantly higher than that in the con-trol group (74.67%, 56/75), P<0.05; the observation group’s body function and mood and role, social function (P<0.05) were significantly higher than that in the control group. The satisfaction rate of the observation group was 96.00% (72/75), which was significantly higher than that of the control group (82.67%) (62/75), P<0.05.