JCNRJournal of Clinical and Nursing Research2208-36852208-3693Bio-Byword Scientific Publishing Pty. Ltd.10.26689/jcnr.v2i1.277Articlehttps://artdesignp.com/journal/JCNR/2/1/10.26689/jcnr.v2i1.277chenSun Xiu2018212018-01-31Objective: To study the clinical effect of minimally invasive single-segment reduction and internal fixation in patients with thoracolumbar fractures. Methods: From June 2013 to June 2014, 100 patients with thoracolumbar fractures were selected as the subjects and they were randomly divided into observation group (50 cases) and control group (50 cases). The patients in the observation group were treated with minimally invasive single-segment reduction and internal fixation. The patients in the control group were treated with short segmental fixation. The clinical effects of the two groups were compared. Results: There was no significant difference in the compression rate and Cobb angle between the two groups before and after operation (P> 0.05). For all patients who were followed up for the last time, the Cobb angle was significantly lower in the observation group than in the control group (P <0.05). The social function, affective function and physical pain score of the observation group were significantly better than the control group (P <0.05). The amount of bleeding in the observation group was (250.4 ± 41.0) ml, which was significantly lower than that in the control group (267.5 ± 32.8) ml. The time required for the operation was (90.2 ± 35.4) min, which was significantly lower than that of the control group (104.5 ± 22.6) min (P <0.05). After treatment, the prognosis was 70.00% and the excellent and good rate was 98.00%, which was significantly higher than that of the control group (46.00%) and 78.00% (P <0.05). Conclusion: Thoracolumbar fractures in patients with dilated channel minimally invasive single-segment reduction and internal fixation treatment can effectively repair the patient's vertebral height and Cobb angle and the degree of correction after surgery was significantly better, safer and worthy of clinical recommended use.