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<article xsi:noNamespaceSchemaLocation="http://jats.nlm.nih.gov/publishing/1.1/xsd/JATS-journalpublishing1-mathml3.xsd" dtd-version="1.1" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"><front><journal-meta><journal-id journal-id-type="publisher-id">JCNR</journal-id><journal-title-group><journal-title>Journal of Clinical and Nursing Research</journal-title></journal-title-group><issn>2208-3685</issn><eissn>2208-3693</eissn><publisher><publisher-name>Bio-Byword Scientific Publishing Pty. Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.26689/jcnr.v5i4.2277</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title>Clinical Observation of 48 Cases of Black Eye Circle Treated with Modified Yu Rong San Gel Eye Mask</title><url>https://artdesignp.com/journal/JCNR/5/4/10.26689/jcnr.v5i4.2277</url><author>HeJinmei,LiChenglong,LiuYunhua,HuangPing,HeMeng,LiLi,YeJun,JinJuanjuan,GaoLin</author><pub-date pub-type="publication-year"><year>2021</year></pub-date><volume>5</volume><issue>4</issue><history><date date-type="pub"><published-time>2021-08-02</published-time></date></history><abstract>Objective: To observe the clinical effect of modified Yu Rong San gel eye mask in the treatment of dark circles. Methods: 96 cases of patients with dark circles were randomly divided into treatment group and control group. In the control group and the treatment group, the common eye mask and the modified Yu Rong San gel eye mask were applied to the black circle area respectively. After 15min, water was used to wash the face, the application of the mask for one time a day, four weeks, one course, and three courses were observed. Results: After three courses of treatment, the total effective rate of the treatment group was higher than that of the control group (P&amp;lt;0.05); the area of black eye circles in the treatment group was smaller than that before treatment (P&amp;lt;0.05); compared with the control group, the score of black eye circles was lower than that before treatment, the difference was statistically significant (P&amp;lt;0.05). Conclusion: Addition and reduction of Yu Rong San gel eye mask is effective in the treatment of dark circles.</abstract><keywords/></article-meta></front><body/><back><ref-list><ref id="B1" content-type="article"><label>1</label><element-citation publication-type="journal"><p>Sarkar R, Bansal S, 2016, Periorbital Hyperpigmentation: A Comprehensive Review. J Clin</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B2" content-type="article"><label>2</label><element-citation publication-type="journal"><p>Aesthet Dermatol. 9(1): 49-55.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B3" content-type="article"><label>3</label><element-citation publication-type="journal"><p>Ahmed NA, Fatani MI, 2019, Treatment of Periorbital Dark Circles: Comparative Study of</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B4" content-type="article"><label>4</label><element-citation publication-type="journal"><p>Carboxy Therapy vs Chemical Peeling vs Mesotherapy. J Cosmet Dermatol. 18(1):169-175.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B5" content-type="article"><label>5</label><element-citation publication-type="journal"><p>Park SR, et al., 2016, Classification by Causes of Dark Circles and Appropriate Evaluation</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B6" content-type="article"><label>6</label><element-citation publication-type="journal"><p>Method of Dark Circles. Skin Res Technol. 22(3):276-283.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B7" content-type="article"><label>7</label><element-citation publication-type="journal"><p>Mac-Mary S, et al., 2019, Identification of Three Key Factors Contributing to the Aetiology of</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B8" content-type="article"><label>8</label><element-citation publication-type="journal"><p>dark Circles by Clinical and Instrumental Assessments of The Infraorbital Region. Clin Cosmet</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B9" content-type="article"><label>9</label><element-citation publication-type="journal"><p>Investig Dermatol, 12:919-929.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B10" content-type="article"><label>10</label><element-citation publication-type="journal"><p>Sarkar R, Das A., 2018, Periorbital Hyperpigmentation: What Lies Beneath? Indian Dermatol</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B11" content-type="article"><label>11</label><element-citation publication-type="journal"><p>Online J. 9(4):229-230.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B12" content-type="article"><label>12</label><element-citation publication-type="journal"><p>Park KY?Seo SJ, Kim MN, 2018, Treatments of Infra-Orbital Dark Circles by Various</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B13" content-type="article"><label>13</label><element-citation publication-type="journal"><p>Etiologies. Ann Dermatol, 30(5): 522-528.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B14" content-type="article"><label>14</label><element-citation publication-type="journal"><p>Chen YL, 2019, Classification and Evaluation of Periorbital Pigmentation. Journal of Clinical</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B15" content-type="article"><label>15</label><element-citation publication-type="journal"><p>Dermatology, 48 (05): 61-65</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B16" content-type="article"><label>16</label><element-citation publication-type="journal"><p>Ma GL, et al., 2014, Etiology, Diagnosis and Treatment of Black Eye. Chinese Journal of Plastic</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B17" content-type="article"><label>17</label><element-citation publication-type="journal"><p>Surgery, 14 (30): 475</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B18" content-type="article"><label>18</label><element-citation publication-type="journal"><p>Wang Y, Zhu T, Jiang N, 2020, Effect of Subcutaneous Injection of Nano Fat Combined with</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B19" content-type="article"><label>19</label><element-citation publication-type="journal"><p>Injection of Granular Fat in Lacrimal Groove Depression Area on Skin Color of Patients with</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B20" content-type="article"><label>20</label><element-citation publication-type="journal"><p>Lower Eyelid Mixed Dark Circles. Journal of Practical Hospital Clinic, 4: 144-148.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B21" content-type="article"><label>21</label><element-citation publication-type="journal"><p>Momosawa A, et al., 2008, Combined Therapy Using Q-Switched Ruby Laser and Bleaching</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B22" content-type="article"><label>22</label><element-citation publication-type="journal"><p>Distributed under creative commons license 4.0 51 Volume 5; Issue 4</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B23" content-type="article"><label>23</label><element-citation publication-type="journal"><p>Treatment with Tretinoin and Hydroquinone for Periorbital Skin Hyperpigmentation in Asians.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B24" content-type="article"><label>24</label><element-citation publication-type="journal"><p>Plast Reconstr Surg, 121(1): 282-288.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B25" content-type="article"><label>25</label><element-citation publication-type="journal"><p>Khan MH, Sink RK, 2005, Intradermally Focused Infrared Laser Pulses: Thermal Effects at</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B26" content-type="article"><label>26</label><element-citation publication-type="journal"><p>Defined Tissue Depths. Lasers Surg Med. 36(4):270-280.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B27" content-type="article"><label>27</label><element-citation publication-type="journal"><p>Chen SZ, 2015, Clinical Study on the Treatment of Black Eye Circles with LED Optical Skin</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B28" content-type="article"><label>28</label><element-citation publication-type="journal"><p>Therapeutic Apparatus. Guangzhou University of TCM.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B29" content-type="article"><label>29</label><element-citation publication-type="journal"><p>Li BL, Wang JH, Huang LL, et al., 2019, Research progress of TCM gel plaster. Review of</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B30" content-type="article"><label>30</label><element-citation publication-type="journal"><p>medicine, 25 (2): 178-182.</p><pub-id pub-id-type="doi"/></element-citation></ref></ref-list></back></article>
