<?xml version="1.1" encoding="utf-8"?>
<article xsi:noNamespaceSchemaLocation="http://jats.nlm.nih.gov/publishing/1.1/xsd/JATS-journalpublishing1-mathml3.xsd" dtd-version="1.1" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"><front><journal-meta><journal-id journal-id-type="publisher-id">JCNR</journal-id><journal-title-group><journal-title>Journal of Clinical and Nursing Research</journal-title></journal-title-group><issn>2208-3685</issn><eissn>2208-3693</eissn><publisher><publisher-name>Bio-Byword Scientific Publishing Pty. Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.26689/jcnr.v6i1.2904</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title>Professor Jun Li Treating Vascular Dementia from Mutual Conclusion of Phlegm and Blood Stasis  </title><url>https://artdesignp.com/journal/JCNR/6/1/10.26689/jcnr.v6i1.2904</url><author>LiHui,LiuWenting,LeiYaling,ZhouHaizhe,WangPei,LiJun</author><pub-date pub-type="publication-year"><year>2022</year></pub-date><volume>6</volume><issue>1</issue><history><date date-type="pub"><published-time>2022-01-19</published-time></date></history><abstract>Professor Jun Li believes that the main etiology and pathogenesis of vascular dementia is the combination of phlegm and blood stasis. The symptoms include feeling faint and declined senses in organs of the head, caused by mystery reason. To cure phlegm and blood stasis simultaneously, the therapy promotes the notion of “resolving phlegm and stimulating the circulation of blood, liberate brain orifices,” and treatments with the addition and removal of “Naotaitong Decoction,” which has an amazing clinical curative effect. This paper examines Professor Jun Li’s theoretical foundations and ideas from the syndrome differentiation and treatment of phlegm and blood stasis, systematically examines the curative effect and mechanism of Naotaitong Decoction in the treatment of vascular dementia, and examines the prescription and medication of typical cases for readers, in the hopes of providing guidance to clinical diagnosis and treatment of this disease.</abstract><keywords/></article-meta></front><body/><back><ref-list><ref id="B1" content-type="article"><label>1</label><element-citation publication-type="journal"><p>Li O, Zhang J, Xu J, 2021, Study on the Mechanism of Xiangxuan Yishen Prescription on Neuronal apoptosis in Vascular Dementia Model Rats. Shaanxi Journal of Traditional Chinese Medicine, 42(06): 687-691 + 704.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B2" content-type="article"><label>2</label><element-citation publication-type="journal"><p>Zhou S, Yu Z, Luo X, 2020, Research Advances in Vascular Dementia. Neural Injury and Functional Reconstruction, 15(12): 729-731.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B3" content-type="article"><label>3</label><element-citation publication-type="journal"><p>Xu X, 2021, Observation on the Curative Effect of Bushen Yizhi Xingnao Decoction on Vascular Dementia and Its Effect on MMSE and HDSADL Score of Vascular Dementia. Chinese Journal of Traditional Medical Science and Technology, 28(04): 614-616.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B4" content-type="article"><label>4</label><element-citation publication-type="journal"><p>Shi M, Zhao M, Zhang J, et al. Mesh Meta-analysis of Oral Chinese Patent Medicine in the Adjuvant Treatment of Vascular Dementia[J]. Chinese Herbal Medicine, 2021, 52(13): 3994-4006.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B5" content-type="article"><label>5</label><element-citation publication-type="journal"><p>Guan Y, Zhong Y, Mao M, et al., 2021, Discussion on the Treatment of Vascular Dementia from “Blood Stasis and Poison.” Jiangsu Journal of Traditional Chinese Medicine, 53(08): 64-67.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B6" content-type="article"><label>6</label><element-citation publication-type="journal"><p>Chan ES, Bautista DT, Zhu Y, et al., 2018, Traditional Chinese Herbal Medicine for Vascular Dementia. Cochrane Database Syst Rev. 12(12): CD010284.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B7" content-type="article"><label>7</label><element-citation publication-type="journal"><p>Shi Y, Cao C, Han Z, et al., 2019, An Herbal Medicine Formula, Ameliorates Cognitive Deficits via Modulating Metabolism of Beta Amyloid Protein and Neurotrophic Factors in Hippocampus of A?1-42 Induced Cognitive Deficit Mice. Front Pharmacol. 10: 258.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B8" content-type="article"><label>8</label><element-citation publication-type="journal"><p>Mo Q, Hao E, Qin W, et al., 2020, Research Progress on Material Basis and Pharmacological Action of Traditional Chinese Medicine for Promoting Blood Circulation and Removing Stasis. Chinese Journal of Experimental Traditional Medical Formulae, 26(01): 205-216.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B9" content-type="article"><label>9</label><element-citation publication-type="journal"><p>Du SQ, Wang X R, Xiao L Y, et al., 2016, Molecular Mechanisms of Vascular Dementia: What can be Learned from Animal Models of Chronic Cerebral Hypoperfusion?. Molecular Neurobiology, 54(5): 3670-3682.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B10" content-type="article"><label>10</label><element-citation publication-type="journal"><p>Li J, Shi G, Zhang X, 2013, Construction of the Theoretical System of Brain and Viscera in Traditional Chinese Medicine and Its Clinical Application. Journal of Shaanxi College of Traditional Chinese Medicine, 36(03): 5-8.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B11" content-type="article"><label>11</label><element-citation publication-type="journal"><p>Li J, 2002, Treatment of Brain Phlegm and Blood Stasis Syndrome. Journal of Shaanxi College of Traditional Chinese Medicine, (02): 1-3.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B12" content-type="article"><label>12</label><element-citation publication-type="journal"><p>Lei Y, Li S, Li J, 2010, Brief Analysis of Professor Li Jun’s Discussion on the Treatment of Encephalopathy with Phlegm and Blood Stasis. Modern Traditional Chinese Medicine, 30(03): 6-7.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B13" content-type="article"><label>13</label><element-citation publication-type="journal"><p>Lin R, 2020, Clinical Effect of Fuyang Warming Kidney Prescription on Vascular Dementia with Yang Deficiency and Phlegm Stasis. Guangxi University of Chinese Medicine.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B14" content-type="article"><label>14</label><element-citation publication-type="journal"><p>Fu X, 2017, Clinical Experimental Study on Syndrome Type of Alzheimer’s Disease in Traditional Chinese Medicine and Classification of Abnormal Body fluid Typing in Uygur Medicine. Xinjiang Medical University.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B15" content-type="article"><label>15</label><element-citation publication-type="journal"><p>Wang K, 2014, Standards of Diagnosis and Treatment. People’s Medical Publishing House, Beijing.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B16" content-type="article"><label>16</label><element-citation publication-type="journal"><p>Wei Y, 2009, Traditional Chinese Medicinal Research, China Press of Traditional Chinese Medicine, Beijing.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B17" content-type="article"><label>17</label><element-citation publication-type="journal"><p>Han H, Gong H, Zhang Y, et al., 2021, Clinical Study of Shenqi Jiangzhuo Decoction in the Treatment of Vascular Dementia with Phlegm and Turbid Obstruction. Global Traditional Chinese Medicine, 14(05): 0595-0597.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B18" content-type="article"><label>18</label><element-citation publication-type="journal"><p>Yang C, 2020, Mechanism of Ditan Decoction in the Treatment of Vascular Dementia Model Rats Based on Inflammatory Response, Oxidative Stress and mirNA-124 /BACE1/A? Pathway. Hubei University of Chinese Medicine.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B19" content-type="article"><label>19</label><element-citation publication-type="journal"><p>Wang J, Shi A, Zhou H, et al., 2021, Effect of Tongqiaobu Decoction on Cognitive Function of Rats with Vascular Dementia. Hunan Journal of Traditional Chinese Medicine, 37(06): 171-173.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B20" content-type="article"><label>20</label><element-citation publication-type="journal"><p>Qi M, Wu H, Tong J, et al., 2021, Study on the Mechanism of Danshensu Improving the Cognitive Function of Vascular Dementia Model Mice through PI3K/Akt Signaling Pathway. Zhejiang Journal of Integrated Traditional Chinese and Western Medicine, 31(04): 314-318.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B21" content-type="article"><label>21</label><element-citation publication-type="journal"><p>Yu T, 2010, Orthodox Tradition of Medicine. Shanxi Science and Technology Publishing House, Taiyuan.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B22" content-type="article"><label>22</label><element-citation publication-type="journal"><p>Chao Y, 2011, General Treatise on the Cause and Symptoms of Diseases. China Medical Science Press, Beijing.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B23" content-type="article"><label>23</label><element-citation publication-type="journal"><p>Du K, Li J, 2004, Effects of Naotaitong Granule on Learning and Memory and AchE Content in Cerebral Cortex of Rats with Vascular Dementia. Study Journal of Traditional Chinese Medicine, (11): 2080-2081 + 2100.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B24" content-type="article"><label>24</label><element-citation publication-type="journal"><p>Zhou H, Yua P, Li J, 2005, Effects of Naotaitong Granule on Body State and SS Content in Hippocampus of Vascular Dementia Rats. Chinese Journal of Basic Medicine in Traditional Chinese Medicine, (08): 583-584.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B25" content-type="article"><label>25</label><element-citation publication-type="journal"><p>Zhou H, Yuan P, Li J, 2007, Clinical Observation on the Treatment of Vascular Dementia with Naotaitong Granule. Liaoning Journal of Traditional Chinese Medicine, (02): 176-177.</p><pub-id pub-id-type="doi"/></element-citation></ref></ref-list></back></article>
