JCNRJournal of Clinical and Nursing Research2208-36852208-3693Bio-Byword Scientific Publishing Pty. Ltd.10.26689/jcnr.v6i3.3933ArticleResearch Progress in TCM Treatment of Retinitis Pigmentosahttps://artdesignp.com/journal/JCNR/6/3/10.26689/jcnr.v6i3.3933YangQianqian,ZhangLi,ChengJinhan,TongJingan2022632022-05-19Retinitis pigmentosa (RP) is a genetic eye disease characterized by primary dystrophic degenerative lesions of photoreceptor cells and retinal pigment epithelium. Although there are many treatment methods, there is still a lack of effective methods to restore visual acuity and visual field. Traditional Chinese medicine ophthalmologists have been conducting extensive clinical research on retinitis pigmentosa for a long time and have achieved significant progress. The paper is a summary of the progress of traditional Chinese medicine in the treatment of retinitis pigmentosa in the last five years.

Yang P, Fan X, (eds) 2018, Ophthalmology, Version 9, People’s Health Publishing House, Beijing.

Peng Q, 2019, Ophthalmology of Traditional Chinese Medicine, Shanghai Science and Technology Press, Shanghai.

Yao Z, Peng J, Wang Y, et al., 2020, Clinical Study on Ziyin Mingmu Pill in the treatment of Retinitis Pigmentosa. Asia Pacific Traditional Medicine, 16(04): 105-107.

Fan M, Zhang X, 2018, Clinical Effective Rate of Modified Zhujing Pill in the Treatment of Primary Retinitis Pigmentosa and Its Effect on Patients’ Visual Acuity. Electronic Journal of Clinical Medical Literature, 5(98): 164-165.

Wang K, 2018, Effect of Zhujing Pill on Primary Retinitis Pigmentosa. China People’s Health Medicine, 30(05): 87, 90.

Luo X, Zhou Z, Duan J, 2017, Effect of Mingmu Dihuang Decoction on Primary Retinitis Pigmentosa in 28 Cases. Hunan Journal of Traditional Chinese Medicine, 33(05): 75-76.

Liu Y, Zhang YZ, Zhang Q, 2017, Treatment of Primary Retinitis Pigmentosa by Ginkgo Mingmufang. Journal of Changchun University of Traditional Chinese Medicine, 33(01): 115-117.

Jiang P, Peng J, Zeng, et al., 2020, Effect of Yiqi Mingmu Pill on Ocular Hemodynamics in Patients with Retinitis Pigmentosa. Journal of Nanjing University of Traditional Chinese Medicine, 36(01): 24-27.

Zhao Y, Han D, 2015, Observation on the Therapeutic Effect of “Erlong Xizhu” Acupuncture on Retinitis Pigmentosa. China Acupuncture and Moxibustion, 35(07): 681-684.

Zhang YJ, Fang XL, 2015, Clinical Observation of Warm Acupuncture in the Treatment of Primary Retinitis Pigmentosa. Chinese Journal of Ophthalmology, 25(04): 259-262.

Tian QM, Qian JC, Bi AL, et al., 2020, Research Progress on the Mechanism of Acupuncture to Improve Vision in Functional Eye Disease. Liaoning Journal of Traditional Chinese Medicine, 47(04): 203-206.

Xu H, Min Z, Lv T, et al., 2016, Clinical Observation on Acupuncture Treatment of Primary Retinitis Pigmentosa. Shanghai Journal of Acupuncture and Moxibustion, 35(04): 395-398.

Yu Z, Ye X, Peng J, et al., 2019, Clinical Observation of Acupuncture Combined with Acupoint Injection in Primary Retinitis Pigmentosa Patients. Liaoning Journal of Traditional Chinese Medicine, 46(04): 816-818.

Huang L, Liu J, 2020, Liu Jingxia Differentiation and Treatment of Retinitis Pigmentosa and Its Clinical Significance. China Journal of Traditional Chinese Medicine Ophthalmology, 30(11): 788-792.

Fang S, 2020, The Clinical Effect of Siwu Wuzi Decoction Combined with Acupuncture in the Treatment of Retinitis Pigmentosa, Jiangxi University of Chinese Medicine.

Zhou XL, Kong L, 2018, Clinical Observation of Wuzi Mingmu Prescription Combined with Acupuncture in the Treatment of Retinitis Pigmentosa. Hebei Med, 24(09): 1564-1568.

Wu D, Wu L, 2018, Clinical Observation of Strengthening Spleen, Tonifying Kidney and Clearing Collaterals Combined with Acupuncture in Treatment of Primary Retinitis Pigmentosa. Beijing Journal of Traditional Chinese Medicine, 37(09): 882-884.

Guo JY, 2015, Effect of Acupuncture Differentiation on 18 Cases of Retinitis Pigmentosa. Contemporary Medicine, 21(23): 152-153.

Jiang C, 2020, Effect of Acupuncture Combined with Mingmu Dihuang Decoction on Retinitis Pigmentosa, Hunan Great Learning of Chinese Medicine.

Xiao XY, 2019, Clinical Observation of Traditional Chinese Medicine Triple Therapy for Primary Retinitis Pigmentosa, Heilongjiang Big Study of Traditional Chinese Medicine.

Chen F, 2016, Effect of Integrated Traditional Chinese and Western Medicine on Retinitis Pigmentosa. Shanxi Traditional Chinese Medicine, 32(03): 26, 29.

Liu H, Li Z, Ji J, et al., 2016, Therapeutic Effect of Supplementing Qi and Activating Blood Circulation Combined with Superior Rectus bypass in the Treatment of Primary Retinitis Pigmentosa. New Traditional Chinese Medicine, 48(10): 148-149.

Li D, Luo J, Mo G, et al., 2017, Clinical Analysis of 61 Cases of Retinitis Pigmentosa Treated by Impact Therapy of Traditional Chinese and Western Medicine. World Update Medical Information Digest, 17(33): 137, 140.

Jiang P, Ou C, Peng J, et al., 2021, Effect of Lycium and Miltiorrhiza on the Expression of Caspase-8, Caspase-12, Caspase-3 and ?B-crystallin in Retina of rd10 Mice. Chinese Journal of Traditional Chinese Medicine Information, 2022(2): 48-54. https://doi.org/10.19879/j.cnki.1005-5304.202105502

Ou C, Peng J, Jiang P, et al., 2020, Effects of Lycium and Miltiorrhiza on Photoreceptor Apoptosis and Oxidative Stress in rd10 Mice. Shi Zhen, Guo Yi Guo Yao, 31(11): 2580-2582

Wang Y, Jiang P, Pan K, et al., 2018, Effects of Yiqi Mingmu Pill on the Expression of Bax and Caspase-3 in Retina of Retinitis Pigmentosa Rats. Advances in Ophthalmology, 38(11): 1019-1023.

Jiang P, Wang Y, Pan K, et al., 2018, Effects of Yiqi Mingmu Pill on the Expression of Bax mRNA and Caspase-3 mRNA in Retina of Retinitis Pigmentosa Rats. World Science and Technology – Modernization of Traditional Chinese Medicine, 20(10): 1834-1839.

Jiang P, Wang Y, Pan K, et al., 2019, Effect of Yiqi Mingmu Pill on the Expression of Fas and FasL Protein in Retina of Rats with Retinitis Pigmentosa. Journal of Traditional Chinese Medicine, 60(04): 327-332.

Li X, Tang Y, Xu K, et al., 2018, Effects of Bushen Yijing Recipe on the Recruitment of Peripheral Blood Stem Cells in the Retina of RCS Rats and the Expression of Ciliary Neurotrophic Factor. Chinese Journal of Ophthalmic Optics and Visual Science, 20(08): 475-483.

Liang L, Li X, Xu K, et al., 2018, Inhibitory Effect of Bushen Yijing Recipe on Photoreceptor Cell Apoptosis in RCS Rats with Congenital Retinitis Pigmentosa. New Progress in Ophthalmology, 38(07): 611-615.