JCNRJournal of Clinical and Nursing Research2208-36852208-3693Bio-Byword Scientific Publishing Pty. Ltd.10.26689/jcnr.v7i5.5392ArticleA Case Study of Severe QT Interval Prolongation Caused by Antidepressantshttps://artdesignp.com/journal/JCNR/7/5/10.26689/jcnr.v7i5.5392FangChao,XiaoNuan,ZhaoHongmei,RenSimin,TanLili,WuJiannan2023752023-09-22QT interval prolongation can be categorized into primary and secondary types according to its etiology. In this paper, we report a case of severe asymptomatic QT interval prolongation secondary to antidepressants. Regular follow-up and electrocardiogram monitoring is crucial when applying antidepressants, especially for patients without cardiac symptoms. This article presents case studies and examines existing literature on long QT syndrome to enhance the diagnosis and management of QT interval prolongation. This is especially relevant for non-psychiatric healthcare professionals who need to be attentive to the side effects of antidepressants to prevent potential adverse consequences resulting from oversight.

Tang J, Zhou J, 2014, Diagnosis and Treatment of Long QT Syndrome. Advances in Cardiovascular Diseases, 33(2): 237–242.

Barsheshet A, Dotsenko O, Goldenberg I, 2013, Genotype Specific Risk Stratification and Management of Patients with Long QT Syndrome. Ann Noninvasive Electrocardiol, 18(6): 499–509.

Schwartz PJ, Crotti L, Insolia R, 2012, Long-QT Syndrome: From Genetics to Management. Circ Arrhythm Electrophysiol, 5(4): 868–877.

Ma H, Li G, Wu J, et al., 2017, A Case of Long QT Syndrome. Chinese Journal of Hypertension, 25(9): 895–897.

Pan M, Zhang S, Wang C, et al., 2011, Effects of Psychosocial Intervention on One-Year Outcomes of First-Episode Elderly Patients with Depression. Chinese Journal of Practical Medicine, 38(13): 5–8.

Zhang M, Han L, Ding X, et al., 2013, Effects of Four Antipsychotic Drugs on the QT Interval of Electrocardiogram in Female Schizophrenia Patients. Journal of Psychiatry, 26(6): 457–459.

Tian F, Gong X, 2011, Clinical Analysis of Electrocardiogram Abnormalities Caused by Antipsychotic Drugs. Journal of Clinical Psychiatry, 21(3): 203.

Tan Y, Zhang S, Chen Y, 2004, QT Interval Prolongation and Torsade De Pointes Caused by Antidepressants and Antipsychotic Drugs. Chinese Journal of Neuropsychiatric Diseases, 2004(05): 403–405.

Vieweg WVR, 2002, Mechanisms and Risks of Electrocardiographic QT Interval Prolongation when Using Antipsychotic Drugs. J Clin Psychiatry, 63(Suppl 9): 18.