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<article xsi:noNamespaceSchemaLocation="http://jats.nlm.nih.gov/publishing/1.1/xsd/JATS-journalpublishing1-mathml3.xsd" dtd-version="1.1" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"><front><journal-meta><journal-id journal-id-type="publisher-id">JCNR</journal-id><journal-title-group><journal-title>Journal of Clinical and Nursing Research</journal-title></journal-title-group><issn>2208-3685</issn><eissn>2208-3693</eissn><publisher><publisher-name>Bio-Byword Scientific Publishing Pty. Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.26689/jcnr.v8i1.5870</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title>Clinical Efficacy Analysis of Tiotropium Bromide Combined with Budesonide and Formoterol Inhalation in Treating COPD</title><url>https://artdesignp.com/journal/JCNR/8/1/10.26689/jcnr.v8i1.5870</url><author>LinHailing,LvYanjie</author><pub-date pub-type="publication-year"><year>2024</year></pub-date><volume>8</volume><issue>1</issue><history><date date-type="pub"><published-time>2024-01-18</published-time></date></history><abstract>Objective: To analyze the clinical efficacy of tiotropium bromide (TB) combined with budesonide formoterol (BUD/FM) inhalation in treating chronic obstructive pulmonary disease (COPD). Methods: 62 COPD patients admitted to the hospital between June 2020 and December 2022 were selected as samples for this study. The patients were divided into a combination group and a conventional group using the random number table method, with 31 cases in each group. The patients in the combination group were treated with TB combined with BUD/FM inhalation, whereas the patients in the conventional group were treated with BUD/FM inhalation only. The treatment efficacy and changes in lung function indicators of both groups were compared. Results: The total efficacy of treatment in the combined group was higher than that in the conventional group, and the difference was statistically significant (P &amp;lt; 0.05). Before treatment, there was no difference in pulmonary function indicators between the two groups (P &amp;gt; 0.05). After three months of treatment, all lung function indicators of the combined group were higher than those of the conventional group, and the difference was statistically significant (P &amp;lt; 0.05). Conclusion: Combining TB with BUD/FM inhalation therapy increases the efficacy of treatment for patients with COPD. Besides, it also improves lung function and leads to a better prognosis.</abstract><keywords/></article-meta></front><body/><back><ref-list><ref id="B1" content-type="article"><label>1</label><element-citation publication-type="journal"><p>Shi H, Yun C, Wei H, et al., 2020, Clinical Observation of Tiotropium Bromide Combined with Budesonide and Formoterol in Treating Asthma-COPD Overlap Syndrome. 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