<?xml version="1.1" encoding="utf-8"?>
<article xsi:noNamespaceSchemaLocation="http://jats.nlm.nih.gov/publishing/1.1/xsd/JATS-journalpublishing1-mathml3.xsd" dtd-version="1.1" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"><front><journal-meta><journal-id journal-id-type="publisher-id">JCNR</journal-id><journal-title-group><journal-title>Journal of Clinical and Nursing Research</journal-title></journal-title-group><issn>2208-3685</issn><eissn>2208-3693</eissn><publisher><publisher-name>Bio-Byword Scientific Publishing Pty. Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.26689/jcnr.v8i10.8500</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title>Evaluating the Impact of Transcutaneous Electrical Nerve Stimulation on Patients Undergoing Inguinal Hernia Surgery: A Meta-Analysis of Randomized Controlled Trials</title><url>https://artdesignp.com/journal/JCNR/8/10/10.26689/jcnr.v8i10.8500</url><author>LiJunfeng,ZhaoXinghao,WeiLunwu,LiHuiping</author><pub-date pub-type="publication-year"><year>2024</year></pub-date><volume>8</volume><issue>10</issue><history><date date-type="pub"><published-time>2024-10-25</published-time></date></history><abstract>Objective: A comprehensive meta-analysis based on the latest randomized controlled trials (RCTs) was conducted to investigate the effects of transcutaneous electrical nerve stimulation (TENS) on patients undergoing treatment after inguinal hernia surgery. Methods: A detailed search of Embase, PubMed, Web of Science, and the Cochrane Library was performed for RCTs investigating the use of TENS during inguinal hernia surgery up to September 28, 2021. The Cochrane tool was applied to assess the risk of bias in the included studies. Results: Seven eligible RCTs with a total of 379 cases were included. The meta-analysis showed a mean difference (MD) in VAS of -1.61 [95% CI: -2.20 – -1.02, P &amp;lt; 0.00001] at 2 hours post-operation, VAS MD = -1.33 at 4 hours post-operation [95% CI: -2.84 – -0.18, P = 0.09], VAS MD = -2.36 at 8 hours post-operation [95% CI: -4.04 – -0.69, P = 0.006], and VAS MD = -1.75 at 24 hours post-operation [95% CI: -2.64 – -0.85, P = 0.0001]. The cortisol level MD at 24 hours post-operation was -52.56 [95% CI: -168.8 – -63.76, P = 0.38]. Conclusion: TENS significantly reduces postoperative pain following inguinal hernia surgery and promotes patient recovery. TENS is recommended for patients undergoing inguinal hernia surgery. However, further high-quality studies are needed to confirm additional effects.</abstract><keywords/></article-meta></front><body/><back><ref-list><ref id="B1" content-type="article"><label>1</label><element-citation publication-type="journal"><p>Kingsnorth A, LeBlanc K, 2003, Hernias: Inguinal and Incisional. Lancet, 362(9395): 1561–1571. https://doi.org/10.1016/S0140-6736(03)14746-0</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B2" content-type="article"><label>2</label><element-citation publication-type="journal"><p>Poulose BK, Shelton J, Phillips S, et al., 2012, Epidemiology and Cost of Ventral Hernia Repair: Making the Case for Hernia Research. Hernia, 16(2): 179–183. https://doi.org/10.1007/s10029-011-0879-9</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B3" content-type="article"><label>3</label><element-citation publication-type="journal"><p>Apfelbaum JL, Chen C, Mehta SS, et al., 2003, Postoperative Pain Experience: Results from A National Survey Suggest Postoperative Pain Continues to be Undermanaged. Anesth Analg, 97(2): 534–540. https://doi.org/10.1213/01.ANE.0000068822.10113.9E</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B4" content-type="article"><label>4</label><element-citation publication-type="journal"><p>Rutter PC, Murphy F, Dudley HA, 1980, Morphine: Controlled Trial of Different Methods of Administration for Postoperative Pain Relief. Br Med J, 280(6206): 12–13. https://doi.org/10.1136/bmj.280.6206.12</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B5" content-type="article"><label>5</label><element-citation publication-type="journal"><p>White PF, 2002, The Role of Non-Opioid Analgesic Techniques in the Management of Pain After Ambulatory Surgery. Anesth Analg, 94(3): 577–585. https://doi.org/10.1097/00000539-200203000-00019</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B6" content-type="article"><label>6</label><element-citation publication-type="journal"><p>Velasco F, 2000, Neuromodulation: An Overview. Arch Med Res, 31(3): 232–236. https://doi.org/10.1016/s0188-4409(00)00063-1</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B7" content-type="article"><label>7</label><element-citation publication-type="journal"><p>Greathouse DG, 1996, Electrotherapeutic Terminology in Physical Therapy. Journal of Orthopaedic &amp; Sports Physical Therapy, 23(4): 233. https://doi.org/10.2519/JOSPT.1996.23.4.233</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B8" content-type="article"><label>8</label><element-citation publication-type="journal"><p>Yılmaz E, Karakaya E, Baydur H, et al., 2019, Effect of Transcutaneous Electrical Nerve Stimulation on Postoperative Pain and Patient Satisfaction. Pain Manag Nurs, 20(2): 140–145. https://doi.org/10.1016/j.pmn.2018.06.003</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B9" content-type="article"><label>9</label><element-citation publication-type="journal"><p>Coutaux A, 2017, Non-Pharmacological Treatments for Pain Relief: TENS and Acupuncture. Joint Bone Spine, 84(6): 657–661. https://doi.org/10.1016/j.jbspin.2017.02.005</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B10" content-type="article"><label>10</label><element-citation publication-type="journal"><p>Jones I, Johnson MI, 2009, Transcutaneous Electrical Nerve Stimulation. Continuing Education in Anaesthesia Critical Care &amp; Pain, 9(4): 130–135. https://doi.org/10.1093/bjaceaccp/mkp021</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B11" content-type="article"><label>11</label><element-citation publication-type="journal"><p>Ahmed MT, 2010, Effect of Transcutaneous Electrical Nerve Stimulation on Postoperative Pain after Inguinal Hernia Repair: A Randomized Placebo-Controlled Trial. Turkish Journal of Physical Medicine and Rehabilitation, 56: 170–176.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B12" content-type="article"><label>12</label><element-citation publication-type="journal"><p>DeSantana JM, Santana-Filho VJ, Guerra DR, et al., 2008, Hypoalgesic Effect of the Transcutaneous Electrical Nerve Stimulation Following Inguinal Herniorrhaphy: A Randomized, Controlled Trial. J Pain, 9(7): 623–629. https://doi.org/10.1016/j.jpain.2008.01.337</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B13" content-type="article"><label>13</label><element-citation publication-type="journal"><p>Dias M, Carneiro NM, Guerra LA, et al., 2010, Effects of Electroacupuncture on Local Anaesthesia for Inguinal Hernia Repair: A Randomised Placebo-Controlled Trial. Acupunct Med, 28(2): 65–70. https://doi.org/10.1136/aim.2009.000570</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B14" content-type="article"><label>14</label><element-citation publication-type="journal"><p>Eidy M, Fazel MR, Janzamini M, et al., 2016, Preemptive Analgesic Effects of Transcutaneous Electrical Nerve Stimulation (TENS) on Postoperative Pain: A Randomized, Double-Blind, Placebo-Controlled Trial. Iran Red Crescent Med J, 18(4): e35050. https://doi.org/10.5812/ircmj.35050</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B15" content-type="article"><label>15</label><element-citation publication-type="journal"><p>Parseliunas A, Paskauskas S, Kubiliute E, et al., 2021, Transcutaneous Electric Nerve Stimulation Reduces Acute Postoperative Pain and Analgesic Use After Open Inguinal Hernia Surgery: A Randomized, Double-Blind, Placebo-Controlled Trial. J Pain, 22(5): 533–544. https://doi.org/10.1016/j.jpain.2020.11.006</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B16" content-type="article"><label>16</label><element-citation publication-type="journal"><p>Szmit M, Agrawal S, Goździk W, et al., 2021, Transcutaneous Electrical Acupoint Stimulation Reduces Postoperative Analgesic Requirement in Patients Undergoing Inguinal Hernia Repair: A Randomized, Placebo-Controlled Study. J Clin Med, 10(1): 146. https://doi.org/10.3390/jcm10010146</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B17" content-type="article"><label>17</label><element-citation publication-type="journal"><p>Jauregui JJ, Cherian JJ, Gwam CU, et al., 2016, A Meta-Analysis of Transcutaneous Electrical Nerve Stimulation for Chronic Low Back Pain. Surg Technol Int, 28: 296–302.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B18" content-type="article"><label>18</label><element-citation publication-type="journal"><p>Zhu Y, Feng Y, Peng L, 2017, Effect of Transcutaneous Electrical Nerve Stimulation for Pain Control After Total Knee Arthroplasty: A Systematic Review and Meta-Analysis. J Rehabil Med, 49(9): 700–704. https://doi.org/10.2340/16501977-2273</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B19" content-type="article"><label>19</label><element-citation publication-type="journal"><p>Maeda Y, Lisi TL, Vance CG, et al., 2007, Release of GABA and Activation of GABA(A) in the Spinal Cord Mediates the Effects of TENS in Rats. Brain Res, 1136(1): 43–50. https://doi.org/10.1016/j.brainres.2006.11.061</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B20" content-type="article"><label>20</label><element-citation publication-type="journal"><p>Sluka KA, Deacon M, Stibal A, et al., 1999, Spinal Blockade of Opioid Receptors Prevents the Analgesia Produced by TENS in Arthritic Rats. J Pharmacol Exp Ther, 289(2): 840–846.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B21" content-type="article"><label>21</label><element-citation publication-type="journal"><p>Emanuelsson BM, Persson J, Alm C, et al., 1997, Systemic Absorption and Block After Epidural Injection of Ropivacaine in Healthy Volunteers. Anesthesiology, 87(6): 1309–1317. https://doi.org/10.1097/00000542-199712000-00008</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B22" content-type="article"><label>22</label><element-citation publication-type="journal"><p>Benedetti F, Amanzio M, Casadio C, et al., 1997, Control of Postoperative Pain by Transcutaneous Electrical Nerve Stimulation After Thoracic Operations. Ann Thorac Surg, 63(3): 773–776. https://doi.org/10.1016/s0003-4975(96)01249-0</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B23" content-type="article"><label>23</label><element-citation publication-type="journal"><p>Mata J, Cabrera S, Sanchís P, et al., 2015, Electro-Acupuncture for Treatment of Knee Pain from Osteoarthritis and the Possible Endocrinology Changes: A Study Protocol for A Randomized Controlled Trial. Trials, 16: 248. https://doi.org/10.1186/s13063-015-0766-2</p><pub-id pub-id-type="doi"/></element-citation></ref></ref-list></back></article>
