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<article xsi:noNamespaceSchemaLocation="http://jats.nlm.nih.gov/publishing/1.1/xsd/JATS-journalpublishing1-mathml3.xsd" dtd-version="1.1" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"><front><journal-meta><journal-id journal-id-type="publisher-id">JCNR</journal-id><journal-title-group><journal-title>Journal of Clinical and Nursing Research</journal-title></journal-title-group><issn>2208-3685</issn><eissn>2208-3693</eissn><publisher><publisher-name>Bio-Byword Scientific Publishing Pty. Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.26689/jcnr.v8i11.7962</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title>A Case Report of Disseminated Nocardiosis</title><url>https://artdesignp.com/journal/JCNR/8/11/10.26689/jcnr.v8i11.7962</url><author>PangRong,WangLingwei</author><pub-date pub-type="publication-year"><year>2024</year></pub-date><volume>8</volume><issue>11</issue><history><date date-type="pub"><published-time>2024-11-26</published-time></date></history><abstract>Objective: To summarize the clinical characteristics and treatment plan for a case of disseminated nocardiosis. Methods: The study summarized the clinical characteristics and treatment plan for a case of disseminated nocardiosis. Results: The primary symptoms of the patient included high fever and multiple enlarged lymph nodes. Chest computed tomography revealed a shadow of nodules in the upper lobe of the left lung, multiple nodules, and pleural effusion in both lungs. Additionally, bilateral blood cultures indicated the presence of Nocardia terpenica. The final diagnosis was disseminated Nocardia sp. infection. Upon admission, anti-infective treatment was initiated with sulfamethoxazole and linezolid. Conclusion: In patients with normal immune function, disseminated nocardiosis may present as high fever with lymph node enlargement, necessitating differentiation from lymphoma. This study reports on the diagnosis and treatment plan of a case of disseminated nocardiosis to enhance understanding and clinical management of this disease.</abstract><keywords/></article-meta></front><body/><back><ref-list><ref id="B1" content-type="article"><label>1</label><element-citation publication-type="journal"><p>Han Y, Cheng M, Li Z, et al., 2024, Clinical Characteristics and Drug Resistance of Nocardia in Henan, China, 2017–2023. Ann Clin Microbiol Antimicrob, 23(1): 23. https://doi.org/10.1186/s12941-024-00677-4</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B2" content-type="article"><label>2</label><element-citation publication-type="journal"><p>Wang C, Sun Q, Yan J, et al., 2023, The Species Distribution and Antimicrobial Resistance Profiles of Nocardia Species in China: A Systematic Review and Meta-Analysis. PLoS Negl Trop Dis, 17(7): e0011432. https://doi.org/10.1371/journal.pntd.0011432</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B3" content-type="article"><label>3</label><element-citation publication-type="journal"><p>Hoshino Y, Watanabe K, Iida S, et al., 2007, Nocardia terpenica sp. nov., Isolated from Japanese Patients with Nocardiosis. International Journal of Systematic and Evolutionary Microbiology, 57(7): 1456–1460. https://doi.org/10.1099/ijs.0.64695-0</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B4" content-type="article"><label>4</label><element-citation publication-type="journal"><p>Gupta S, Grant LM, Powers HR, et al., 2023, Invasive Nocardia Infections across Distinct Geographic Regions, United States. Emerg Infect Dis, 29(12): 2417–2425. https://doi.org/10.3201/eid2912.230673</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B5" content-type="article"><label>5</label><element-citation publication-type="journal"><p>Lee HN, Do KH, Kim EY, et al., 2024, Comparative Analysis of CT Findings and Clinical Outcomes in Adult Patients With Disseminated and Localized Pulmonary Nocardiosis. J Korean Med Sci, 39(11): e107. https://doi.org/10.3346/jkms.2024.39.e107</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B6" content-type="article"><label>6</label><element-citation publication-type="journal"><p>Soueges S, Bouiller K, Botelho-Nevers E, et al., 2022, Prognosis and Factors Associated with Disseminated Nocardiosis: A Ten-Year Multicenter Study. J Infect, 85(2): 130–136. https://doi.org/10.1016/j.jinf.2022.05.029</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B7" content-type="article"><label>7</label><element-citation publication-type="journal"><p>Presant CA, Wiernik PH, Serpick AA, 1973, Factors Affecting Survival in Nocardiosis. Am Rev Respir Dis, 108(6): 1444–1448. https://doi.org/10.1164/arrd.1973.108.6.1444</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B8" content-type="article"><label>8</label><element-citation publication-type="journal"><p>Liu P, Wang Z, Jian Z, et al., 2023, The Clinical Characteristic and Management of Patients with Nocardiosis in a Tertiary Hospital in China. J Microbiol Biotechnol, 33(5): 574–581. https://doi.org/10.4014/jmb.2209.09034</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B9" content-type="article"><label>9</label><element-citation publication-type="journal"><p>Saubolle MA, Sussland D, 2003, Nocardiosis: Review of Clinical and Laboratory Experience. J Clin Microbiol, 41(10): 4497–4501. https://doi.org/10.1128/JCM.41.10.4497-4501.2003</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B10" content-type="article"><label>10</label><element-citation publication-type="journal"><p>Margalit I, Lebeaux D, Tishler O, et al., 2021, How Do I Manage Nocardiosis? Clin Microbiol Infect, 27(4): 550–558. https://doi.org/10.1016/j.cmi.2020.12.019</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B11" content-type="article"><label>11</label><element-citation publication-type="journal"><p>Balachandar A, Zhabokritsky A, Matukas LM, 2020, Disseminated Nocardiosis with Multisite Involvement in An Immunocompetent Patient. CMAJ, 192(33): E956–E959. https://doi.org/10.1503/cmaj.200153</p><pub-id pub-id-type="doi"/></element-citation></ref></ref-list></back></article>
