JCNRJournal of Clinical and Nursing Research2208-36852208-3693Bio-Byword Scientific Publishing Pty. Ltd.10.26689/jcnr.v8i11.8945ArticleStudy on the Anti-Radiation Function of Selenium-Enriched Agaricus blazei Murill Polysaccharides and Tea Polyphenol Compound Solutionhttps://artdesignp.com/journal/JCNR/8/11/10.26689/jcnr.v8i11.8945ZhouXu,ChiXinming,WangLan,JuHaiyang20248112024-11-27Mice were administered a selenium-rich Agaricus blazei Murill (Se-AbM) polysaccharides and tea polyphenol compound solution for prevention and treatment. Following exposure to 2 Gy of infrared radiation, peripheral blood counts of white blood cells, red blood cells, and platelets were assessed, along with serum levels of apoptosis-related factors Fas and Fas ligand, inflammatory factors interferon-gamma and tumor necrosis factor-alpha, immune-related factors interleukin-3 and interleukin-6, and indicators of oxidative stress, including malondialdehyde, superoxide dismutase, and glutathione. The results showed significant differences in these indicators between the Se-AbM-treated group and the model group, suggesting that Se-AbM may inhibit apoptosis, enhance the clearance of free radicals in the body, improve antioxidant capacity, and provide a significant protective effect against radiation-induced immune damage.

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