JCNRJournal of Clinical and Nursing Research2208-36852208-3693Bio-Byword Scientific Publishing Pty. Ltd.10.26689/jcnr.v8i5.6983ArticleDiscussion on Traditional Chinese Medicine Treatment of Liver-Depression-Spleen-Deficiency Type Insomnia Based on the State-Target Theory and the Regulation of Microbiome-Gut-Brain Axishttps://artdesignp.com/journal/JCNR/8/5/10.26689/jcnr.v8i5.6983WuKai,GongYongjie,YangShan,YuYalan2024852024-06-14Insomnia has become an urgent clinical problem in modern society. Current research has found that the gut flora-gut-brain axis plays an important role in regulating insomnia. The state-target theory is a product of the combination of traditional Chinese medicine and modern molecular biology technology. This paper clarifies the correlation between the state-target theory, the intestinal flora-gut-brain axis, and liver-depression-spleen-deficiency insomnia. The use of traditional Chinese medicine to regulate the structure and abundance of intestinal flora was also explored, aiming to integrate traditional Chinese medicine with Western medicine for the prevention and treatment of liver-depression-spleen-deficiency insomnia.

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