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<article xsi:noNamespaceSchemaLocation="http://jats.nlm.nih.gov/publishing/1.1/xsd/JATS-journalpublishing1-mathml3.xsd" dtd-version="1.1" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"><front><journal-meta><journal-id journal-id-type="publisher-id">JCNR</journal-id><journal-title-group><journal-title>Journal of Clinical and Nursing Research</journal-title></journal-title-group><issn>2208-3685</issn><eissn>2208-3693</eissn><publisher><publisher-name>Bio-Byword Scientific Publishing Pty. Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.26689/jcnr.v8i5.7357</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title>Effects of Progressive Muscle Relaxation Training on Anxiety, Depression, and Quality of Life in Patients with Cerebral Small Vessel Disease</title><url>https://artdesignp.com/journal/JCNR/8/5/10.26689/jcnr.v8i5.7357</url><author>ShiChengwen,ZhaoFeifan,WangYingshuo,LiuChengxuan,MaoAiyu,JinSiqi</author><pub-date pub-type="publication-year"><year>2024</year></pub-date><volume>8</volume><issue>5</issue><history><date date-type="pub"><published-time>2024-06-24</published-time></date></history><abstract>Objective: To explore the effects of progressive muscle relaxation training on anxiety, depression, and quality of life in patients with cerebral small vessel disease (CSVD). Methods: Sixty-one patients with CSVD in the Department of Neurology of a tertiary hospital were divided into an observation group (28 patients) and a control group (33 patients) by lottery method. The control group received conventional nursing care, while the observation group received progressive muscle relaxation training interventions in addition to the conventional care. The Hamilton Anxiety Scale (HAMA), the Hamilton Depression Scale (HAMD), and the Stroke-Specific Quality of Life Scale (SS-QOL) were used to compare the effects before the intervention, 7 days after the intervention, and 30 days after the intervention. Results: Over time, at different time points after the intervention, the anxiety and depression scores of patients with CSVD in the observation group were significantly lower than those in the control group (P &amp;lt; 0.05). The quality of life scores were significantly higher in the observation group compared to the control group (P &amp;lt; 0.05), and these differences were statistically significant. Conclusion: Progressive muscle relaxation training can improve anxiety and depression in patients with cerebral small vessel disease and can effectively enhance their quality of life.</abstract><keywords/></article-meta></front><body/><back><ref-list><ref id="B1" content-type="article"><label>1</label><element-citation publication-type="journal"><p>Skrobot OA, Black SE, Chen C, et al., 2018, Progress Toward Standardized Diagnosis of Vascular Cognitive Impairment: Guidelines from the Vascular Impairment of Cognition Classification Consensus Study. 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