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<article xsi:noNamespaceSchemaLocation="http://jats.nlm.nih.gov/publishing/1.1/xsd/JATS-journalpublishing1-mathml3.xsd" dtd-version="1.1" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"><front><journal-meta><journal-id journal-id-type="publisher-id">JCNR</journal-id><journal-title-group><journal-title>Journal of Clinical and Nursing Research</journal-title></journal-title-group><issn>2208-3685</issn><eissn>2208-3693</eissn><publisher><publisher-name>Bio-Byword Scientific Publishing Pty. Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.26689/jcnr.v8i5.7360</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title>The Effect of the Direct Anti-Human Globulin Test on the Clinical Outcome of Patients Receiving Blood Transfusion</title><url>https://artdesignp.com/journal/JCNR/8/5/10.26689/jcnr.v8i5.7360</url><author>NiuBen,WangLe</author><pub-date pub-type="publication-year"><year>2024</year></pub-date><volume>8</volume><issue>5</issue><history><date date-type="pub"><published-time>2024-06-24</published-time></date></history><abstract>Objective: To study the effect of the direct anti-human globulin test on the clinical efficacy of blood transfusion patients. Methods: 52 transfused patients were selected for this study, of which 26 cases with positive direct anti-human globulin tests were included in the positive group, and another 26 cases with negative direct anti-human globulin tests were included in the negative group. The apparent efficacy of the patients in the two groups after blood transfusion was compared. Results: After blood transfusion, the apparent efficacy of the negative group was significantly higher, P &amp;lt; 0.05; in the positive group, the proportion of the predominantly multi-antibody group was the highest; after blood transfusion, the post-transfusion apparent efficacy of the simple IgG group was higher than that of the multi-antibody group, P &amp;lt; 0.05; comparing the intensity of the different antibodies resulted in the 1+ group, and the 3+ to 4+ groups were significantly lower after blood transfusion, P &amp;lt; 0.05. Conclusion: The use of the direct antiglobulin test in transfused patients showed that patients with positive results would have better clinical efficacy. Direct anti-human globulin tests will have an impact on the clinical efficacy of blood transfusion in patients with positive results, so it is very important to carry out a direct anti-human globulin test on blood transfusion patients.</abstract><keywords/></article-meta></front><body/><back><ref-list><ref id="B1" content-type="article"><label>1</label><element-citation publication-type="journal"><p>Duan B, Wang S, Lian J, et al., 2021, Clinical Significance of Direct Anti-Human Globulin Test in the Efficacy of Blood Transfusion in Patients. Clinical Blood Transfusion and Testing, 23(02): 189–191.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B2" content-type="article"><label>2</label><element-citation publication-type="journal"><p>Su R, Hu M, Zhao G, et al., 2023, Impact of Direct Anti-Human Globulin Test on the Clinical Efficacy of Blood Transfusion Patients. Electronic Journal of Modern Medicine and Health Research, 7(16): 141–144.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B3" content-type="article"><label>3</label><element-citation publication-type="journal"><p>Wei D, Cao C, Li S, 2023, Study on the Relationship Between Positive Typing of Direct Anti-Human Globulin Test and Efficacy of Blood Transfusion. Journal of Aerospace Medicine, 34(07): 779–782.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B4" content-type="article"><label>4</label><element-citation publication-type="journal"><p>Kang X, Peng W, Wei S, 2022, Discussion on the Relationship Between Positive Typing of Direct Anti-Human Globulin Test and the Efficacy of Blood Transfusion. Clinical Blood Transfusion and Laboratory, 24(03): 338–342.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B5" content-type="article"><label>5</label><element-citation publication-type="journal"><p>Jia B, Qiao S, 2022, Analysis of the Clinical Value of Pre-Transfusion Irregular Antibody Screening and Direct Anti-Human Globulin Test. China Practical Medicine, 17(14): 85–87.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B6" content-type="article"><label>6</label><element-citation publication-type="journal"><p>Qiu C, Wang Y, Fu X, et al., 2023, Evaluation of Disease Distribution and Transfusion Efficacy in Patients with Positive Direct Anti-Human Globulin Test. Clinical Medicine Research and Practice, 8(15): 17–20.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B7" content-type="article"><label>7</label><element-citation publication-type="journal"><p>Wu F, Xu Y, Liao R, 2023, Diagnostic Value of Direct Anti-Human Globulin Test and Irregular Antibody Screening for Hemolytic Disease in Newborns. Journal of Clinical and Experimental Medicine, 22(15): 1653–1656.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B8" content-type="article"><label>8</label><element-citation publication-type="journal"><p>Yin X, Quan J, Chai F, 2023, Clinical Study on Cross-Matching Method for Direct Anti-Human Globulin Test-Positive Patients. Health Home, 2023(9): 108–110.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B9" content-type="article"><label>9</label><element-citation publication-type="journal"><p>Wang M, Yan X, 2022, Comparison of the Application Effect of Microplate Polyglutamine Method and Anti-Human Globulin Microplate Method in Pre-Transfusion Irregular Antibody Screening. Clinical Medicine Research and Practice, 7(21): 114–117.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B10" content-type="article"><label>10</label><element-citation publication-type="journal"><p>Wu HE, 2022, Comparison of the Value of Anti-Human Globulin Microcolumn Gel Method and Coagulant Amine Method for Crossmatching. Chinese Journal of Modern Medicine, 24(5): 75–77.</p><pub-id pub-id-type="doi"/></element-citation></ref></ref-list></back></article>
