<?xml version="1.1" encoding="utf-8"?>
<article xsi:noNamespaceSchemaLocation="http://jats.nlm.nih.gov/publishing/1.1/xsd/JATS-journalpublishing1-mathml3.xsd" dtd-version="1.1" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"><front><journal-meta><journal-id journal-id-type="publisher-id">JCNR</journal-id><journal-title-group><journal-title>Journal of Clinical and Nursing Research</journal-title></journal-title-group><issn>2208-3685</issn><eissn>2208-3693</eissn><publisher><publisher-name>Bio-Byword Scientific Publishing Pty. Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.26689/jcnr.v8i8.7424</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title>Clinical Effectiveness of Dienogest in the Treatment of Endometriosis</title><url>https://artdesignp.com/journal/JCNR/8/8/10.26689/jcnr.v8i8.7424</url><author>LiQiumin,LiuFeifei</author><pub-date pub-type="publication-year"><year>2024</year></pub-date><volume>8</volume><issue>8</issue><history><date date-type="pub"><published-time>2024-08-28</published-time></date></history><abstract>Objective: This paper aims to investigate the efficacy of desogestrel in the treatment of endometriosis. Methods: In this study, 61 patients with endometriosis in our hospital from January 2023 to December 2023 were selected and divided using the random sampling method. All the patients were treated with desogestrel and the pain symptom scores and HDL-C (high-density lipoprotein cholesterol) levels of the patients were compared before and after the treatment. The treatment effects and adverse effects during the administration of the drug were closely observed. Results: After the patients were treated with desogestrel, the effective rate of treatment was as high as 98.36%, and the incidence of adverse reactions during treatment was 6.55%. Compared with the pre-treatment period, the scores of various pain symptoms were significantly reduced and the HDL-C level was improved after treatment, with P &amp;lt; 0.05. Conclusion: Desogestrel showed significant efficacy in the treatment of endometriosis, effectively relieving patients’ pain while elevating HDL-C levels. In addition, the incidence of adverse reactions to this drug is relatively low, which is worth utilizing.</abstract><keywords/></article-meta></front><body/><back><ref-list><ref id="B1" content-type="article"><label>1</label><element-citation publication-type="journal"><p>Yao HL, Liang NN, 2023, Effectiveness of Mifepristone Combined with Dienogest in the Treatment of Dysmenorrhea in Endometriosis. Clinical Medical Eng, 30(10): 1399–1400.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B2" content-type="article"><label>2</label><element-citation publication-type="journal"><p>Li L, Wang A, Peng L, 2023, Observation on the Clinical Effect of Warming Menstruation and Resolving Symptoms in Combination with Desogestrel in the Treatment of Endometriosis. Chinese Journal of Family Planning, 31(10): 2443–2446 + 2451.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B3" content-type="article"><label>3</label><element-citation publication-type="journal"><p>Tian H, 2023, Effect of Dienogest Drug Treatment of Ovarian Endometriosis on Cyst Diameter, Associated Pain and Ovarian Reserve. Harbin Medicine, 43(05): 20–22.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B4" content-type="article"><label>4</label><element-citation publication-type="journal"><p>Chen Y, Feng C, 2023, Treatment of Endometriosis by Gui Zhi Fu Ling Wan Combined with Desogestrel and Improvement of Endometrial Receptivity. China Drugs &amp; Clinics, 23(07): 461–465.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B5" content-type="article"><label>5</label><element-citation publication-type="journal"><p>Shao L, Wang H, Yang Z, 2023, Effect of Dienogest Combined with Laparoscopic Surgery for the Treatment of Endometriosis Infertility on Patients’ Serum AMH, VEGF and Clinical Pregnancy. Chinese Journal of Family Planning, 31(11): 2593–2596 + 2600.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B6" content-type="article"><label>6</label><element-citation publication-type="journal"><p>Huang WR, Mi JF, 2023, Comparison of Efficacy and Safety Between Dienogest and Gonadotropin-Releasing Hormone Agonist Combined with Laparoscopic Surgery for Endometriosis. Clinical Rational Drug Use, 16(33): 104–107.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B7" content-type="article"><label>7</label><element-citation publication-type="journal"><p>Wang HY, 2023, Effect of Dienogest on Recurrence and Ovarian Reserve Function After Laparoscopic Surgery in Patients with Endometriotic Cysts of the Ovary in Reproductive Age. China Practical Medicine, 18(19): 95–98.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B8" content-type="article"><label>8</label><element-citation publication-type="journal"><p>Ren H, Liu M, Dong X, et al., 2023, New Progress of Dienogest in the Pharmacologic Treatment of Endometriosis. Maternal and Child Health Care of China, 38(19): 3839–3842.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B9" content-type="article"><label>9</label><element-citation publication-type="journal"><p>Luo Y, Huang Z, Lei J, et al., 2023, Analysis of High-Risk Factors for the Clinical Outcome of Levonorgestrel Intrauterine Device System Combined with Dienogest in the Treatment of Adenomyosis. Clinical Misdiagnosis and Mistreatment, 36(09): 72–77.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B10" content-type="article"><label>10</label><element-citation publication-type="journal"><p>Wu WT, Shen QL, Dong J, et al., 2023, Effect of Dienogest on Improving Lesion Size and Clinical Efficacy of Sex Hormone Levels in Patients with Endometriosis. Maternal and Child Health Care of China, 38(17): 3199–3202.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B11" content-type="article"><label>11</label><element-citation publication-type="journal"><p>Cheng J, Hong N, 2023, Effect of Drospirenone Ethinyl Estradiol and Dienogest Combined with Surgery in the Treatment of Endometriosis and Its Effect on Serum Estrogen and Menstrual Flow. Chinese Journal of Family Planning, 31(08): 1893–1896.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B12" content-type="article"><label>12</label><element-citation publication-type="journal"><p>Zhang S, Chang R, Guo C, 2023, Laparoscopic Surgery Combined with Anti-Infection and Dienogest Treatment. A Clinical Study of Endometriosis. Journal of Localized Surgery, 32(08): 708–711.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B13" content-type="article"><label>13</label><element-citation publication-type="journal"><p>Feng D, 2023, A Comparison of Dienogest and GnRH-a for the Treatment on Maintenance Therapy of Endometriosis After Fertility-Preserving Surgery: A Meta-Analysis, Master’s thesis, Jiamusi University.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B14" content-type="article"><label>14</label><element-citation publication-type="journal"><p>Ling X, Chen J, 2023, Clinical Effect of Dienogest in Conservative Treatment of Ovarian Endometriosis Cyst. Maternal and Child Health Care of China, 38(24): 4879–4883.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B15" content-type="article"><label>15</label><element-citation publication-type="journal"><p>Guo D, 2023, Analysis of the Effect and Recurrence Rate of Laparoscopy Combined with Dienogest in the Treatment of Ovarian Endometriosis. Journal of Women’s and Children’s Health, 2(06): 45–47 + 50.</p><pub-id pub-id-type="doi"/></element-citation></ref></ref-list></back></article>
