JCNRJournal of Clinical and Nursing Research2208-36852208-3693Bio-Byword Scientific Publishing Pty. Ltd.10.26689/jcnr.v9i11.13010ArticleAnalysis of the Efficacy of High-Flow Nasal Cannula Oxygen Therapy and Non-Invasive Ventilation in COPD Patients https://artdesignp.com/journal/JCNR/9/11/10.26689/jcnr.v9i11.13010YinXue,LiYan,MaYan,SunYue,LiLi,YanWenmei,ZhangJianhua,ZhangHe,YangHaisheng20259112025-12-10Patients with acute exacerbation of chronic obstructive pulmonary disease (COPD) often suffer from respiratory failure and require respiratory support therapy. High-flow nasal cannula oxygen therapy (HFNC) and non-invasive positive pressure ventilation (NIPPV) are commonly used non-invasive respiratory support methods. HFNC can provide precisely heated and humidified high-flow oxygen, reducing dead space and increasing alveolar ventilation. NIPPV can supply stable high-concentration oxygen and improve gas exchange. This article reviews the application of HFNC and NIPPV in the acute exacerbation stage of COPD, aiming to provide references for reasonable clinical selection.

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