JCNRJournal of Clinical and Nursing Research2208-36852208-3693Bio-Byword Scientific Publishing Pty. Ltd.10.26689/jcnr.v9i12.13418ArticleThe Application Value of Droplet Digital PCR Technology in the Diagnosis of Bacterial Infections in Febrile Patientshttps://artdesignp.com/journal/JCNR/9/12/10.26689/jcnr.v9i12.13418ZengYan20259122025-12-31Droplet digital PCR (ddPCR), as the third-generation PCR technology, demonstrates significant advantages in the etiological diagnosis of infectious diseases due to its absolute quantification, ultra-high sensitivity, and multiplex detection capabilities. This article reports a case of a patient with fever of unknown origin, where ddPCR rapidly confirmed a drug-resistant bacterial infection and dynamically monitored treatment efficacy. Combining literature evidence, this paper systematically elaborates on the technical principles, clinical performance, and practical value of ddPCR in febrile patients.

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