JCNRJournal of Clinical and Nursing Research2208-36852208-3693Bio-Byword Scientific Publishing Pty. Ltd.10.26689/jcnr.v9i12.13482ArticleThe Impact of Prophylactic Antibiotic Use in Emergency Treatment of Acute Pancreatitis on the Incidence of Infectious Pancreatic Necrosis https://artdesignp.com/journal/JCNR/9/12/10.26689/jcnr.v9i12.13482ZhouJianguo20259122025-12-31Objective: To analyze the value of prophylactic antibiotic use in reducing the incidence of pancreatic necrosis in patients with emergency acute pancreatitis (AP). Methods: A total of 70 AP patients who sought medical attention from January 2024 to January 2025 were randomly divided into groups by drawing lots. Group A received prophylactic antibiotic intervention, while Group B received conventional intervention. Results: Group A demonstrated superior outcomes compared to Group B in terms of therapeutic efficacy, duration of symptoms, inflammatory factors, symptom scores, and complication rates, with p < 0.05. Conclusion: Prophylactic antibiotic treatment in emergency AP patients leads to a decrease in inflammatory factor levels, alleviation of symptoms, a reduction in the incidence of infectious pancreatic necrosis, and is safe and effective.

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