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<article xsi:noNamespaceSchemaLocation="http://jats.nlm.nih.gov/publishing/1.1/xsd/JATS-journalpublishing1-mathml3.xsd" dtd-version="1.1" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"><front><journal-meta><journal-id journal-id-type="publisher-id">JCNR</journal-id><journal-title-group><journal-title>Journal of Clinical and Nursing Research</journal-title></journal-title-group><issn>2208-3685</issn><eissn>2208-3693</eissn><publisher><publisher-name>Bio-Byword Scientific Publishing Pty. Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.26689/jcnr.v9i3.10075</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title>Application Research of Continuous Ambulatory Peritoneal Dialysis and Automated Peritoneal Dialysis Machine in Patients with End-Stage Renal Disease Undergoing Peritoneal Dialysis</title><url>https://artdesignp.com/journal/JCNR/9/3/10.26689/jcnr.v9i3.10075</url><author>MuHuihui,WangJinjin</author><pub-date pub-type="publication-year"><year>2025</year></pub-date><volume>9</volume><issue>3</issue><history><date date-type="pub"><published-time>2025-04-03</published-time></date></history><abstract>This study analyzed the therapeutic effects of continuous ambulatory peritoneal dialysis (CAPD) and automated peritoneal dialysis (APD) on patients with end-stage renal disease. Fifty patients admitted between January 2024 and December 2024 were randomly assigned to two groups, with the observation group receiving APD and the reference group receiving CAPD. Renal function indicators, nutritional indicators, mineral metabolism, urine volume, and ultrafiltration volume changes were compared between the two groups. After treatment, the observation group showed lower renal function indicators, higher nutritional indicators, and better mineral metabolism levels compared to the reference group (P &amp;lt; 0.05). While there was no significant difference in urine volume between the two groups (P &amp;gt; 0.05), the observation group demonstrated superior ultrafiltration volume (P &amp;lt; 0.05). 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