<?xml version="1.1" encoding="utf-8"?>
<article xsi:noNamespaceSchemaLocation="http://jats.nlm.nih.gov/publishing/1.1/xsd/JATS-journalpublishing1-mathml3.xsd" dtd-version="1.1" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"><front><journal-meta><journal-id journal-id-type="publisher-id">JCNR</journal-id><journal-title-group><journal-title>Journal of Clinical and Nursing Research</journal-title></journal-title-group><issn>2208-3685</issn><eissn>2208-3693</eissn><publisher><publisher-name>Bio-Byword Scientific Publishing Pty. Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.26689/jcnr.v9i3.10106</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title>Ambulatory Blood Pressure Characteristics and Risk Factors for Circadian Rhythm Abnormalities in Elderly Patients with Hypertension</title><url>https://artdesignp.com/journal/JCNR/9/3/10.26689/jcnr.v9i3.10106</url><author>HuangYaqian</author><pub-date pub-type="publication-year"><year>2025</year></pub-date><volume>9</volume><issue>3</issue><history><date date-type="pub"><published-time>2025-04-04</published-time></date></history><abstract>Objective: To analyze the characteristics of ambulatory blood pressure in elderly patients with hypertension and find out the risk factors of abnormal circadian rhythm. Methods: According to the circadian rhythm of patients’ blood pressure, they were divided into group A, group B, and group C, and all the data of hypertension patients in this study were collected, including age, gender, BMI, smoking, drinking, basic diseases (diabetes, cerebrovascular disease, hyperlipidemia, etc.), fasting blood glucose, ambulatory blood pressure (24-hour mean systolic pressure, 24-hour mean diastolic pressure, daytime mean systolic pressure and daytime mean diastolic pressure). Results: There were significant differences in mean systolic blood pressure and mean diastolic blood pressure at night among group A, group B and group C (P &amp;lt; 0.05). Age, hyperlipidemia and fasting blood glucose were risk factors for circadian rhythm abnormality (P &amp;lt; 0.05), and 24-hour urinary sodium was a protective factor for circadian rhythm abnormality (P &amp;lt; 0.05). Conclusion: Age, hyperlipidemia and fasting blood glucose are risk factors for circadian rhythm abnormality (P &amp;lt; 0.05), and 24-hour urinary sodium is a protective factor for circadian rhythm abnormality (P &amp;lt; 0.05).</abstract><keywords/></article-meta></front><body/><back><ref-list><ref id="B1" content-type="article"><label>1</label><element-citation publication-type="journal"><p>Kim BK, Lim YH, Lee HT, et al., 2011, Non-dipper Pattern is a Determinant of the Inappropriateness of Left Ventricular Mass in Essential Hypertensive Patients. Korean Circulation Journal, 41(4): 191–197.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B2" content-type="article"><label>2</label><element-citation publication-type="journal"><p>Eleni K, Efstathios M, Vassilios R, et al., 2011, Dipping Status and Hostility in Newly Diagnosed Essential Hypertension. The International Journal of Psychiatry in Medicine, 42(2): 181–194.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B3" content-type="article"><label>3</label><element-citation publication-type="journal"><p>Li B, Lai C, Qi L, 2008, Circadian Rhythm Characteristics and Clinical Significance of Blood Pressure in Elderly Patients with Hypertension. Sichuan Medical Journal, 29(1): 50–51.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B4" content-type="article"><label>4</label><element-citation publication-type="journal"><p>Yang K, Zhu X, Feng Y, et al., 2020, Abnormal Blood Pressure Circadian Rhythms Are Relevant to Cerebral Infarction and Leukoaraiosis in Hypertensive Patients. BMC Neurol, 20(1): 36. DOI: 10.1186/s12883-020-1626-6.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B5" content-type="article"><label>5</label><element-citation publication-type="journal"><p>Takahiro K, Satoshi H, Yuda T, et al., 2023, Cognitive Impairment in Heart Failure Patients: Association with Abnormal Circadian Blood Pressure Rhythm: A Review from the HOPE Asia Network. Hypertension Research: Official Journal of the Japanese Society of Hypertension, 47(2): 261–270.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B6" content-type="article"><label>6</label><element-citation publication-type="journal"><p>Velarie BA, LK K, 2023, Associations between Circadian Disruption and Cardiometabolic Disease Risk: A Review. Obesity (Silver Spring, Md.), 31(3): 615–624.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B7" content-type="article"><label>7</label><element-citation publication-type="journal"><p>China Hypertension Prevention and Control Guidelines Revision Committee, Hypertension Union (China), Cardiovascular Branch of Chinese Medical Association, et al., 2019, China Hypertension Prevention and Control Guidelines (Revised in 2018). Chinese Journal of Cardiovascular Medicine, 24(1): 24–56.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B8" content-type="article"><label>8</label><element-citation publication-type="journal"><p>Tanner MR, Jaeger CB, Bradley KC, et al., 2024, Blood Pressure on Ambulatory Monitoring and Risk for Cardiovascular Disease and All-cause Mortality: Ecological Validity or Measurement Reliability? American Journal of Hypertension, 38(2): 111–119.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B9" content-type="article"><label>9</label><element-citation publication-type="journal"><p>El N J, GT B, Jordana C, et al., 2023, Prognostic Utility of Rhythmic Components in 24-hour Ambulatory Blood Pressure Monitoring for the Risk Stratification of Chronic Kidney Disease Patients with Cardiovascular Co-morbidity. medRxiv: The Preprint Server for Health Sciences, 2023.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B10" content-type="article"><label>10</label><element-citation publication-type="journal"><p>Yancui S, Ying Z, Fei L, et al., 2023, The Relationship between Circadian Rhythm of Blood Pressure and Vascular Dysfunction in Essential Hypertension. Clinical and Experimental Hypertension (New York, N.Y.: 1993), 45(1): 2229535–2229535.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B11" content-type="article"><label>11</label><element-citation publication-type="journal"><p>Kim Y, Kim J, Joh IR, et al., 2024, Disrupted Rest-Activity Circadian Rhythms Are Associated with All-cause Mortality in Patients with Chronic Kidney Diseases. Chronobiology International, 41(11): 11–12.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B12" content-type="article"><label>12</label><element-citation publication-type="journal"><p>Line P, MK M, Ulla F, et al., 2021, Brain Tumours in Children and Adolescents May Affect the Circadian Rhythm and Quality of Life. Acta Paediatrica (Oslo, Norway: 1992), 110(12): 3376–3386.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B13" content-type="article"><label>13</label><element-citation publication-type="journal"><p>Poppy N, Elizabeth JG, Ed GR, et al., 2021, Changes in Circadian Rhythms Dysregulate Inflammation in Ageing: Focus on Leukocyte Trafficking. Frontiers in Immunology, 12: 673405–673405.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B14" content-type="article"><label>14</label><element-citation publication-type="journal"><p>Koren D, Knutson LK, Burke KB, et al., 2024, The Association of Self-Reported Sleep and Circadian Measures with Glycemic Control and Diabetes Complications among Young Adults with Type 2 Diabetes. American Journal of Physiology. Heart and Circulatory Physiology, 326(6): H1386-H1395.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B15" content-type="article"><label>15</label><element-citation publication-type="journal"><p>Roberto FSDJ, José FVA, Douglas SDCI, et al., 2023, Non-dipping Circadian Pattern as a Predictor of Incipient Nephropathy in Normotensive Normoalbuminuric Type 1 Diabetics. Chronobiology International, 40(12): 1–6.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B16" content-type="article"><label>16</label><element-citation publication-type="journal"><p>Pablo S, Sreenivas K, Arvind S, et al., 2021, Common Genetic Variation in Circadian Clock Genes Are Associated with Cardiovascular Risk Factors in an African American and Hispanic/Latino Cohort. IJC Heart &amp; Vasculature, 34: 100808.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B17" content-type="article"><label>17</label><element-citation publication-type="journal"><p>Álvarez-Rendón PJ, Riesgo-Escovar RJ, 2020, Circadian and Rhythmic-related Behavioral Co-morbidities of the Diabetic State in Drosophila melanogaster. General and Comparative Endocrinology, 295: 113477.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B18" content-type="article"><label>18</label><element-citation publication-type="journal"><p>Agostino A, Giulia S, Milos A, et al., 2021, Influence of Smoking and Other Cardiovascular Risk Factors on Heart Rate Circadian Rhythm in Normotensive and Hypertensive Subjects. PloS One, 16(9): e0257660.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B19" content-type="article"><label>19</label><element-citation publication-type="journal"><p>Felix LA G, Sousa DA D, Teixeira PS, et al., 2020, Eating Habits, Sleep, and a Proxy for Circadian Disruption Are Correlated with Dyslipidemia in Overweight Night Workers. Nutrition (Burbank, Los Angeles County, Calif.), 83: 111084.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B20" content-type="article"><label>20</label><element-citation publication-type="journal"><p>Ferrell MJ, Chiang YJ, 2015, Circadian Rhythms in Liver Metabolism and Disease. Acta Pharmaceutica Sinica B, 5(2): 113–122.</p><pub-id pub-id-type="doi"/></element-citation></ref></ref-list></back></article>
