JCNRJournal of Clinical and Nursing Research2208-36852208-3693Bio-Byword Scientific Publishing Pty. Ltd.10.26689/jcnr.v9i4.10380ArticleCorrelation of Serum 25-hydroxyvitamin D Levels with Senile Hypertension and Its Strokehttps://artdesignp.com/journal/JCNR/9/4/10.26689/jcnr.v9i4.10380ZangShasha,ZhaoQing,LiuSha,LiZhe2025942025-04-29Objective: Correlation of serum 25-hydroxyvitamin D level with senile hypertension and its stroke. Methods: Two hundred hypertensive patients admitted to the hospital from February 2022 to December 2023 were classified as study subjects. They were divided into grade 2 hypertension group and grade 3 hypertension group, and 100 healthy medical checkups admitted during the same period were analyzed as study subjects. Results: Comparison of diagnostic results between grade 2 hypertension and grade 2 hypertensive stroke patients, there was a difference in 25(OH)D, (P < 0.05). Comparison of test results between grade 3 hypertension and grade 3 hypertensive stroke patients, there was a difference in age, BMI, 25(OH)D, GLU, LDL-C, (P < 0.05). Serum 25-hydroxyvitamin D level is a high-risk factor for the occurrence of stroke in elderly hypertensive patients, so the probability of risk is higher, where 25(OH)D (ng/mL), GLU (mmol/L), there is a difference, (P < 0.05). Conclusion: There is a greater relationship between the occurrence of stroke and serum 25-hydroxyvitamin D level in elderly hypertensive patients. The occurrence of the disease has a greater relationship with this indicator in patients and is also a high-risk factor that affects the patients’ morbidity, so it is necessary to pay attention to the monitoring of this indicator after the onset of the disease in patients.

Zhao Q, Zhu Y, Chen Z, et al., 2023, Correlation Analysis of Serum 25-Hydroxyvitamin D, Cystatin-C, Homocysteine and Hypertension Combined with Osteoporosis. Journal of Naval Medicine, 44(9): 990–994.

Hu Z, Wang J, Zhang Y, et al., 2023, A Cohort Study of Serum 25-Hydroxyvitamin D Levels and Risk of Hypertension in Adults. Abstract Book of the 14th Asian Congress of Nutrition. Asian Federation of Nutrition Societies, Chinese Society of Nutrition.

Yuan Y, Kong F, Chi L, et al., 2023, Correlation Study of Serum 25-Hydroxyvitamin D Level with Senile Hypertension and Its Stroke. Marker Immunoassay and Clinics, 30(4): 568–572.

Yang S, Jiang G, Yang L, et al., 2022, Correlation of Blood Lipids, Blood Uric Acid and Serum 25-Hydroxyvitamin D Levels with Hypertension and Its Disease Grading in the Elderly. Chinese Journal of Gerontology, 42(20): 4915–4917.

Dai C, Li X, Zhao Y, et al., 2019, Study on the Change of Serum 25-Hydroxyvitamin D Level in Hypertension and Its Correlation with Lipid-Related Indexes. Journal of Harbin Medical University, 53(3): 306–309.

Chen K, Ge L, Lin X, 2021, Research Progress of Serum 25-Hydroxyvitamin D and Hypertension. Xinjiang Traditional Chinese Medicine, 39(5): 107–109.

Zeng J, Xiao C, Feng L, 2021, Relationship Between Serum 25-Hydroxyvitamin D Level and Blood Pressure Stratification and Lipid Metabolism Abnormalities in Elderly Hypertensive Patients. Famous Doctors, 2021(10): 122–124.

Ren B, Gao J, 2021, Clinical Significance of Serum 25-Hydroxyvitamin D Test in Patients with Gestational Hypertension. Chinese Drugs and Clinics, 21(5): 806–808.

Shen D, Chen M, Cheng M, et al., 2020, Correlation Study of Serum 25-Hydroxyvitamin D with Hypertension and Its Risk Stratification in the Elderly. Chinese Journal of Geriatric Cardiovascular and Cerebrovascular Disease, 22(9): 983–985.

Liu X, Gong N, 2020, Changes of Serum 25-Hydroxyvitamin D in Patients with Gestational Hypertension and Its Clinical Significance. Journal of Practical Clinical Medicine, 24(9): 66–68, 72.