JCNRJournal of Clinical and Nursing Research2208-36852208-3693Bio-Byword Scientific Publishing Pty. Ltd.10.26689/jcnr.v9i5.10639ArticleObservation on the Effect of Internal Limiting Membrane Flipping and Covering Technique in the Treatment of High Myopic Macular Holehttps://artdesignp.com/journal/JCNR/9/5/10.26689/jcnr.v9i5.10639LiZhiwei2025952025-05-30Objective: To evaluate the effectiveness of the internal limiting membrane (ILM) flipping and covering technique in the treatment of patients with high myopic macular hole (HMMH). Methods: One hundred and two patients with HMMH who were admitted to the hospital from June 2019 to June 2024 were selected. The minimum diameter of the macular hole (MH) in all patients was ≤ 500μm. The patients were randomly divided into two groups. The experimental group received 25G pars plana vitrectomy (PPV) combined with ILM flipping and covering technique, while the reference group received PPV combined with ILM peeling. The efficacy indicators and best corrected visual acuity levels were compared between the two groups. Results: The MH closure rate and retinal reattachment rate were higher in the experimental group than in the reference group at 3 and 6 months postoperatively (P<0.05). The best corrected visual acuity level was higher in the experimental group than in the reference group at 3 and 6 months postoperatively (P < 0.05). The Chinese version of the Visual Function-Related Quality of Life Questionnaire-25 (CVRQOL-25) score was higher in the experimental group than in the reference group at 3 and 6 months postoperatively (P < 0.05). No serious complications were observed in both groups postoperatively, and there was no difference between the two groups (P > 0.05). Conclusion: The ILM flipping and covering technique can improve the MH closure rate and retinal reattachment rate in patients with HMMH (diameter ≤ 500μm), enhance the best corrected visual acuity level, and improve the quality of life related to visual function, with fewer postoperative complications.

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