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<article xsi:noNamespaceSchemaLocation="http://jats.nlm.nih.gov/publishing/1.1/xsd/JATS-journalpublishing1-mathml3.xsd" dtd-version="1.1" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"><front><journal-meta><journal-id journal-id-type="publisher-id">JCNR</journal-id><journal-title-group><journal-title>Journal of Clinical and Nursing Research</journal-title></journal-title-group><issn>2208-3685</issn><eissn>2208-3693</eissn><publisher><publisher-name>Bio-Byword Scientific Publishing Pty. Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.26689/jcnr.v9i6.11050</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title>Social Alienation in Adolescents with Depression from an Interaction Perspective: A Qualitative Research</title><url>https://artdesignp.com/journal/JCNR/9/6/10.26689/jcnr.v9i6.11050</url><author>LiPeiqing,MiaoQunfang,NingHanyi,XuYijing</author><pub-date pub-type="publication-year"><year>2025</year></pub-date><volume>9</volume><issue>6</issue><history><date date-type="pub"><published-time>2025-07-07</published-time></date></history><abstract>Objective: This study aims to explore the experiences of social alienation among adolescents with depression, providing practical This study aims to explore the experiences of social alienation among adolescents with depression, providing practical guidance for improving their interpersonal relationships and facilitating their reintegration into society. Methods: This qualitative research was conducted following the conventional content analysis method. 20 adolescents with depression were employed to select from June to August 2024 for face-to-face semi-structured interviews. The collected data were analyzed using Colaizzi's seven-step method. Results: Three themes and eight sub-themes were analyzed and identified: individual level (feelings of helplessness and powerlessness, cognitive distortion, avoidance and withdrawal), family level (lack of family awareness, family conflict), social level (limitations of academic stress and social circle, lack and degradation of skills, generalization of virtual reality, social “stigma”). Conclusion: Adolescents with depression experience complex social alienation. Healthcare providers should enhance their self-awareness and social adaptation skills, improve family dynamics, and provide a comprehensive range of services and services to help them to cope with the challenges of depression. Healthcare providers should enhance their self-awareness and social adaptation skills, improve family dynamics, strengthen communication, bolster family support systems, and collaborate to develop comprehensive social networks and psychological services. This will create a supportive social atmosphere to help adolescents gradually alleviate their feelings of social alienation.</abstract><keywords/></article-meta></front><body/><back><ref-list><ref id="B1" content-type="article"><label>1</label><element-citation publication-type="journal"><p>Singh S, Zaki R, Farid N, 2019, A Systematic Review of Depression Literacy: Knowledge, Help-Seeking and Stigmatising Attitudes Among Adolescents. 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