JCNRJournal of Clinical and Nursing Research2208-36852208-3693Bio-Byword Scientific Publishing Pty. Ltd.10.26689/jcnr.v9i6.11061ArticleMultimodal MRI Enhancement Combined with Diffusion-Weighted Imaging for the Differential Diagnosis of Non-Lactating Mastitis and Breast Cancerhttps://artdesignp.com/journal/JCNR/9/6/10.26689/jcnr.v9i6.11061WeiYongxiang2025962025-07-07Objective: To explore the value of multimodal MRI enhancement scanning and diffusion-weighted imaging in differentiating non-puerperal mastitis (NPM) and breast cancer. Methods: From September 2022 to September 2024, 56 patients with breast diseases were selected as samples and grouped according to disease type. Twenty-eight patients with breast cancer were included in Group A, and 28 patients with NPM were included in Group B. All patients underwent multimodal MRI enhancement scanning and diffusion-weighted imaging. The MRI results, time-signal intensity curves, ADC values, lesion intensity, and imaging signs were compared between the two groups. Results: There were no significant differences in enhancement characteristics, lymph node enlargement, and margins between Group A and Group B (P > 0.05). The proportion of outflow curves in Group A was higher than that in Group B (P < 0.05). The ADC value in Group A was lower than that in Group B, and the lesion intensity was higher than that in Group B (P < 0.05). There were significant differences in imaging signs, such as abscess or sinus, ascending time-signal curve, and mammary duct dilation between Group A and Group B (P < 0.05). Conclusion: Multimodal MRI enhancement scanning and diffusion-weighted imaging techniques can be used to diagnose breast diseases. Comprehensive analysis of time-signal intensity curves, lesion intensity, imaging signs, and ADC values can differentiate between NPM and breast cancer.

Xu J, Ma G, Liu P, 2024, Evaluation of Axillary Lymph Node Metastasis in Breast Cancer Using Multimodal Magnetic Resonance Imaging. China Medical Equipment, 21(5): 64–68.

Wang C, 2023, Diagnostic Efficacy of Dynamic Contrast-Enhanced MRI Combined With Diffusion-Weighted Imaging for Non-Mass-Like Breast Cancer and Granulomatous Mastitis. Imaging Research and Medical Applications, 7(9): 87–89.

Wang H, Wang Y, Sun X, et al., 2022, Clinical Value of Multimodal Ultrasound Imaging Combined With VEGF and CerbB-2 in Differential Diagnosis of Non-Lactating Mastitis and Breast Cancer. Practical Cancer Magazine, 37(3): 399–403.

Li N, Lu X, Zan X, et al., 2021, Clinical Value of Ultrasound Combined With Elastography in Differential Diagnosis of Non-Lactating Mastitis and Breast Cancer. Journal of Medical Imaging, 31(5): 795–798.

Meng N, 2023, Discussion on the Differential Diagnostic Value of Ultrasonic Imaging Examination for Non-Lactating Mastitis and Breast Cancer. Imaging Research and Medical Applications, 7(10): 42–44.

Tan Y, 2023, Comparative Analysis of Ultrasonic Features of Non-Lactating Mastitis and Breast Cancer. Imaging Research and Medical Applications, 7(7): 158–160.

He Q, Li Y, 2022, Value of Color Doppler Ultrasound in Differential Diagnosis of Breast Cancer and Non-Lactating Breast Inflammatory Masses. Clinical Medical Research and Practice, 7(23): 126–130.

Qiu C, 2022, Application of Color Doppler Ultrasound in Differentiating Breast Cancer From Non-Lactating Breast Inflammatory Masses. Modern Medical Imaging, 31(3): 547–549.

Li W, Liu W, Liang X, et al., 2022, Application of Multimodal Ultrasound in Differential Diagnosis of Non-Mass-Like Breast Cancer and Idiopathic Granulomatous Mastitis. Journal of Harbin Medical University, 56(4): 324–328+333.

Min J, Jiang D, Peng G, et al., 2021, Differential Diagnostic Value of Ultrasonic Multimodal Technology for Non-Lactating Mastitis and Breast Cancer. Chinese Journal of Medical Physics, 38(3): 337–339.