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<article xsi:noNamespaceSchemaLocation="http://jats.nlm.nih.gov/publishing/1.1/xsd/JATS-journalpublishing1-mathml3.xsd" dtd-version="1.1" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"><front><journal-meta><journal-id journal-id-type="publisher-id">JCNR</journal-id><journal-title-group><journal-title>Journal of Clinical and Nursing Research</journal-title></journal-title-group><issn>2208-3685</issn><eissn>2208-3693</eissn><publisher><publisher-name>Bio-Byword Scientific Publishing Pty. Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.26689/jcnr.v9i6.11073</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title>Application and Observation of Inulin in the Treatment of Constipation for Critically Ill Patients in the ICU</title><url>https://artdesignp.com/journal/JCNR/9/6/10.26689/jcnr.v9i6.11073</url><author>PengQiaoyun,WangLianyun</author><pub-date pub-type="publication-year"><year>2025</year></pub-date><volume>9</volume><issue>6</issue><history><date date-type="pub"><published-time>2025-07-08</published-time></date></history><abstract>Objective: To explore the application method and clinical effect of inulin in the treatment of constipation for patients in the ICU. Methods: Sixty ICU patients with constipation were randomly divided into an experimental group and a control group, with 30 patients in each group. The control group received nasal feeding with a regular diet. The experimental group received nasal feeding with a regular diet plus inulin. The defecation status of the patients was observed and compared on the 3rd, 5th, and 7th days. Results: Among the 30 patients in the experimental group and 30 patients in the control group, there was a statistically significant difference in treatment effect between the two groups (P &amp;lt; 0.05). The treatment duration was (3.91 ± 1.09) days in the experimental group and (5.78 ± 1.52) days in the control group. Conclusion: Inulin has a significant effect in the treatment of constipation for critically ill patients in the ICU and is worthy of clinical promotion and application.</abstract><keywords/></article-meta></front><body/><back><ref-list><ref id="B1" content-type="article"><label>1</label><element-citation publication-type="journal"><p>Xiong H, Jiang J, Zou A, et al., 2021, Discussion on the Effect of Inulin-Type Prebiotics on Constipation During Pregnancy. Advances in Clinical Medicine, 11(10): 4519–4522.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B2" content-type="article"><label>2</label><element-citation publication-type="journal"><p>Wang Y, Chen X, Chen Z, et al., 2021, Preparation and Laxative Activity Study of Inulin Composite Chewable Tablets. Food Research and Development, 42(10): 82–86.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B3" content-type="article"><label>3</label><element-citation publication-type="journal"><p>Cui H, Xu L, Liu Y, 2022, Efficacy of Inulin Combined With Conventional Therapy in the Treatment of Nonalcoholic Fatty Liver Disease and Its Effect on Intestinal Flora. Modern Practical Medicine, 34(1): 74–76.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B4" content-type="article"><label>4</label><element-citation publication-type="journal"><p>Wang R, Wang Y, Yang J, et al., 2023, Study on the Regulation of NF-κB Signaling by Inulin to Inhibit Apoptosis and Reduce Inflammatory Bowel Disease in Mice. Medical Journal of the Chinese People’s Armed Police Forces, 34(10): 874–879.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B5" content-type="article"><label>5</label><element-citation publication-type="journal"><p>Niu T, Yang S, Duan H, et al., 2025, Effects of Inulin on the Immune Activity of Macrophage RAW 264.7. Natural Product Research and Development, 37(1): 10–17.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B6" content-type="article"><label>6</label><element-citation publication-type="journal"><p>Ma C, Liu Y, Liu T, et al., 2024, Optimization of Inulin Coarse Grain Biscuit Formula by Response Surface Methodology and Study on Its Laxative Effect. Preservation and Processing, 24(8): 66–73.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B7" content-type="article"><label>7</label><element-citation publication-type="journal"><p>Lan D, Xie X, Mo L, et al., 2024, Effects of Inulin on Redox Status and Intestinal Flora in Mice With Eczema. Modern Food Science and Technology, 40(7): 17–23.</p><pub-id pub-id-type="doi"/></element-citation></ref></ref-list></back></article>
