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<article xsi:noNamespaceSchemaLocation="http://jats.nlm.nih.gov/publishing/1.1/xsd/JATS-journalpublishing1-mathml3.xsd" dtd-version="1.1" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"><front><journal-meta><journal-id journal-id-type="publisher-id">JCNR</journal-id><journal-title-group><journal-title>Journal of Clinical and Nursing Research</journal-title></journal-title-group><issn>2208-3685</issn><eissn>2208-3693</eissn><publisher><publisher-name>Bio-Byword Scientific Publishing Pty. Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.26689/jcnr.v9i6.11108</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title>Research Progress on Epidemiology and Comprehensive Prevention and Control Strategies of HIV Infection</title><url>https://artdesignp.com/journal/JCNR/9/6/10.26689/jcnr.v9i6.11108</url><author>CuiXuancheng</author><pub-date pub-type="publication-year"><year>2025</year></pub-date><volume>9</volume><issue>6</issue><history><date date-type="pub"><published-time>2025-07-08</published-time></date></history><abstract>Acquired Immunodeficiency Syndrome (AIDS) caused by Human Immunodeficiency Virus (HIV) infection poses a serious threat to global public health. This article comprehensively reviews the epidemiological characteristics of HIV infection, including the global and domestic epidemic situation, transmission routes, and characteristics of high-risk groups. It also introduces comprehensive prevention and control strategies in detail. 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