JCNRJournal of Clinical and Nursing Research2208-36852208-3693Bio-Byword Scientific Publishing Pty. Ltd.10.26689/jcnr.v9i7.11485ArticleNursing Care of a Child with Membranous Nephropathy Combined with Cerebral Venous Thrombosishttps://artdesignp.com/journal/JCNR/9/7/10.26689/jcnr.v9i7.11485WangYan,YangManman2025972025-08-04Objective: To explore the key points of holistic nursing for children with membranous nephropathy (MN) combined with cerebral venous thrombosis, providing a reference for similar cases. Methods: The course of illness data of an 8-year-old boy with MN in the recurrent phase complicated with cerebral venous sinus thrombosis (CVST) was retroactively analyzed. Systematic nursing was implemented based on evidence-based practices, including strict neurological monitoring, anticoagulation and thrombolysis medication nursing, fluid and electrolyte management, hypoalbuminemia and edema nursing, complication prevention, and mental health education. Results: After 16 days of continuous infusion of low molecular weight heparin and supportive treatment, the child’s symptoms, such as headache and vomiting, disappeared. The reexamination of MRV showed significant absorption of thrombosis, and there was no residual neurological deficit. During the 3-month follow-up, the anticoagulation compliance was good, and there was no recurrence. Conclusion: Early identification of hypercoagulability risk, strengthening dynamic evaluation of neurological signs and coagulation indicators, standardizing anticoagulation and thrombolysis nursing, and cooperating with continuous health management can significantly improve the prognosis of children with MN combined with CVST.

Wang R, Gao C, Xia Z, 2021, Research Progress on Pediatric Primary Membranous Nephropathy. Journal of Clinical Pediatrics, 39(7): 549.

Chen S, 2020, Study on the Effect of Comprehensive Nursing Intervention on the Recurrence of Nephrotic Syndrome. World Latest Medicine Information (Electronic Version), 20(95): 319–320. DOI: 10.3969/j.issn.1671-3141.2020.95.177

Yang Y, Chen C, Wu P, 2021, Evidence-Based Nursing Practice of Subcutaneous Injection of Low-Molecular-Weight Heparin Calcium. Modern Nurse (First Ten-Day Issue), 28(10): 136–138. DOI: 10.19791/j.cnki.1006-6411.2021.28.051.

Ma D, Wu H, 2023, Study on the Compatibility Taboos and Application Precautions of Mannitol. Chinese Journal of Drug Abuse Prevention and Treatment, 29(6): 963–966. DOI:10.15900/j.cnki.zylf1995.2023.06.012.

Zhang L, Cheng J, Yang J, et al., 2022, The Impact of Rosenthal Effect Nursing on Treatment Compliance and Mental Health of Children With Nephrotic Syndrome. Modern Nurse, 29(5): 97–100. DOI:10.19793/j.cnki.1006-6411.2022.15.028.

Liu X, Feng S, Wang F, et al., 2024, The Impact of Closed-Loop Nursing Combined With Continuing Nursing on Compliance and Abnormal Psychological Behaviors of Children With Nephrotic Syndrome. Comprehensive Nursing Care, 22(3): 501–503.

Wang X, Zhang X, 2021, Exploration of the Application of Continuous Nursing in the Treatment of Children With Nephrotic Syndrome. Modern Clinical Nursing, 40(7): 139–143. DOI:10.16662/j.cnki.1674-0742.2021.07.139.

Guo L, Wang Q, 2024, Application of Family-Hospital Integrated Rehabilitation Nursing Based on Ecosystem Theory in Children With Nephrotic Syndrome. Hainan Medical Journal, 35(15): 2250–2254.

Sun L, Hao S, Zhang W, et al., 2016, A Case Report of 4 Children With Primary Nephrotic Syndrome Complicated by Cerebral Venous Thrombosis. Chinese Journal of Evidence-Based Pediatrics, 11(1): 47–50.