<?xml version="1.1" encoding="utf-8"?>
<article xsi:noNamespaceSchemaLocation="http://jats.nlm.nih.gov/publishing/1.1/xsd/JATS-journalpublishing1-mathml3.xsd" dtd-version="1.1" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"><front><journal-meta><journal-id journal-id-type="publisher-id">JCNR</journal-id><journal-title-group><journal-title>Journal of Clinical and Nursing Research</journal-title></journal-title-group><issn>2208-3685</issn><eissn>2208-3693</eissn><publisher><publisher-name>Bio-Byword Scientific Publishing Pty. Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.26689/jcnr.v9i8.11738</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title>Study on the Value of Bedside Brain Ultrasound Examination in Early Diagnosis of Brain Tissue Injury in Neonates with Intrauterine Distress</title><url>https://artdesignp.com/journal/JCNR/9/8/10.26689/jcnr.v9i8.11738</url><author>YangDan,LiQionglan,XiangXiaoqing</author><pub-date pub-type="publication-year"><year>2025</year></pub-date><volume>9</volume><issue>8</issue><history><date date-type="pub"><published-time>2025-09-04</published-time></date></history><abstract>Objective: To analyze the value of bedside cranial ultrasonography in the early diagnosis of neonatal brain tissue injury in intrauterine distress. Methods: 128 neonates with suspected intrauterine distress admitted to the Yichang Central People’s Hospital from January 2023 to December 2024 were selected as study subjects based on the inclusion and exclusion criteria, and all subjects underwent bedside craniocerebral ultrasonography and MRI, and the results of MRI were used as the gold standard to divide the infants into the brain-injury group (n = 31) and the no-brain-injury The children were divided into brain injury group (n = 31) and no brain injury group (n = 97), and the value of bedside cranial ultrasonography for early diagnosis of brain tissue injury in neonates with intrauterine distress was analyzed. Results: (1) Among the 128 cases of intrauterine distress neonates, 31 cases were examined for abnormal signs, including 22 cases (70.97%) examined by bedside craniocerebral ultrasonography and 28 cases (90.32%) examined by MRI. (2) Bedside cranial ultrasound detected hypoxic-ischemic encephalopathy in 6 cases, accounting for 4.69%, ventricular widening in 2 cases, accounting for 1.56%, intracranial hemorrhage in 8 cases, accounting for 6.25%, periventricular softening of white matter in 5 cases, accounting for 3.91%, and cerebral edema in 1 case, accounting for 0.78%, while MRI detected hypoxic-ischemic encephalopathy in 9 cases, accounting for 7.03%. 3 cases of ventricular widening, accounting for 2.34%, 4 cases of intracranial hemorrhage, accounting for 3.13%, 9 cases of periventricular-intraventricular white matter softening, accounting for 7.03%, and 3 cases of cerebral edema, accounting for 2.34% were examined. Among them, the detection rate of periventricular-intraventricular hemorrhage by bedside cranial ultrasound was significantly higher than that of MRI (P &amp;lt; 0.05). Conclusion: The diagnostic value of bedside cranial ultrasound in periventricular-intraventricular hemorrhage is high, but the diagnostic value is not as good as that of MRI in other brain tissue injuries, and clinically appropriate examination protocols can be selected according to the specific types of craniocerebral injuries.</abstract><keywords/></article-meta></front><body/><back><ref-list><ref id="B1" content-type="article"><label>1</label><element-citation publication-type="journal"><p>Qiu J, Wang C, 2024, Early Diagnostic Value of Craniocerebral Ultrasound for Intrauterine Distress Neonatal Brain Injury. Chinese Journal of Practical Neurological Diseases, 27(3): 307–310.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B2" content-type="article"><label>2</label><element-citation publication-type="journal"><p>Tao X, 2025, Analysis of the Value of Cranial Ultrasound in the Diagnosis of Neonatal Craniocerebral Diseases. China Medical Guide, 23(8): 125–128.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B3" content-type="article"><label>3</label><element-citation publication-type="journal"><p>Tsering D, 2024, Clinical Value of Cranial Ultrasound in the Diagnosis of Neonatal Craniocerebral Injury. Chinese Science and Technology Journal Database (Digest Edition) Medicine and Health, 2024(9): 25–28.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B4" content-type="article"><label>4</label><element-citation publication-type="journal"><p>Zhang C, Wang S, Zhang B, 2024, Analysis of Transcranial Brain Ultrasound Application in Early Diagnosis of Brain Injury in High-Risk Newborns. World Composite Medicine (in Chinese and English), 10(7): 145–148.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B5" content-type="article"><label>5</label><element-citation publication-type="journal"><p>Fang J, Qiu Y, Wang P, 2025, Clinical Value of Cranial Ultrasound in Predicting Neurodevelopment in High-Risk Newborns. Journal of Clinical Ultrasound Medicine, 27(3): 210–214.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B6" content-type="article"><label>6</label><element-citation publication-type="journal"><p>Zhou Y, 2025, Application of Bedside Cranial Ultrasonography in the Diagnosis of Intracranial Hemorrhage in Preterm Infants. China Science and Technology Journal Database Medicine, 2025(1): 73–76.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B7" content-type="article"><label>7</label><element-citation publication-type="journal"><p>Wang YG, Zheng XZ, Lu ZP, et al., 2025, Application of Ultrasound in the Assessment of Intracranial Conditions in Severe Craniocerebral Injury. Chinese Journal of Clinical Neurosurgery, 30(2): 69–72.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B8" content-type="article"><label>8</label><element-citation publication-type="journal"><p>Liu J, Yu H, Mao J, et al, 2012, Expert Consensus on Diagnosis and Prevention of Brain Injury in Preterm Infants. Chinese Journal of Contemporary Pediatrics, 14(12): 2.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B9" content-type="article"><label>9</label><element-citation publication-type="journal"><p>Chen X, Zeng Q, Lin J, et al., 2024, Exploring the Value of Bedside Color Doppler Ultrasound in the Diagnosis of Neonatal Craniocerebral Diseases. Modern Medical Imaging, 33(6): 1125–1127.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B10" content-type="article"><label>10</label><element-citation publication-type="journal"><p>Chen H, 2024, Clinical Application Value of Cranial Ultrasound in the Diagnosis of Neonatal Craniocerebral Diseases. Modern Medical Imaging, 33(6): 1159–1161.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B11" content-type="article"><label>11</label><element-citation publication-type="journal"><p>Wang JH, 2024, Diagnostic Analysis of Intracranial Hemorrhage in Preterm Infants With Different Gestational Ages and Birth Masses by Bedside Cranial Ultrasound. Xinjiang Medicine, 54(1): 50–53.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B12" content-type="article"><label>12</label><element-citation publication-type="journal"><p>Li YK, 2024, Comparison of Diagnostic Value of Intracranial Hemorrhage in Neonates Between Bedside Cranial Ultrasound and CT. China Journal of Practical Medicine, 51(21): 65–68.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B13" content-type="article"><label>13</label><element-citation publication-type="journal"><p>Wang C, Hu Y, Song Y, et al., 2025, Clinical Value of Bedside Cranial Ultrasound in Assessing Hemodynamic Parameters of Intracranial Hemorrhage in Newborns. Journal of Hebei North College (Natural Science Edition), 41(4): 11–13.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B14" content-type="article"><label>14</label><element-citation publication-type="journal"><p>Yan Y, Ji J, Meng K, 2023, Application of Amplitude-Integrated Electroencephalography Combined With Bedside Cranial Ultrasonography in the Assessment of Brain Injury and Brain Development in Preterm Infants. Chinese Science and Technology Journal Database (Full Text Edition) Medicine and Health, 2023(9): 69–72.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B15" content-type="article"><label>15</label><element-citation publication-type="journal"><p>Zhu X, Wu Z, Yue J, 2023, Application Value of Cranial Ultrasound in Early Diagnosis of Neonatal Brain Injury. Clinical Medicine Research and Practice, 8(29): 97–100.</p><pub-id pub-id-type="doi"/></element-citation></ref></ref-list></back></article>
