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<article xsi:noNamespaceSchemaLocation="http://jats.nlm.nih.gov/publishing/1.1/xsd/JATS-journalpublishing1-mathml3.xsd" dtd-version="1.1" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"><front><journal-meta><journal-id journal-id-type="publisher-id">JCNR</journal-id><journal-title-group><journal-title>Journal of Clinical and Nursing Research</journal-title></journal-title-group><issn>2208-3685</issn><eissn>2208-3693</eissn><publisher><publisher-name>Bio-Byword Scientific Publishing Pty. Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.26689/jcnr.v9i9.12275</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title>Innovation in the “Basic-Clinical” Connection Teaching Model of Biochemistry Course Empowered by AI Case-Guided Learning System</title><url>https://artdesignp.com/journal/JCNR/9/9/10.26689/jcnr.v9i9.12275</url><author>ShiYungang,JiaMeixia,WangChangfeng</author><pub-date pub-type="publication-year"><year>2025</year></pub-date><volume>9</volume><issue>9</issue><history><date date-type="pub"><published-time>2025-10-16</published-time></date></history><abstract>Against the background of the continuous reform in medical education, biochemistry, as a fundamental medical course, maintains a close connection with clinical practice. However, under the traditional teaching model, the effectiveness of the “basic-clinical” connection is relatively poor, which hinders the improvement of educational outcomes. In the practical teaching of higher vocational medical education, the integration of the AI Case-Guided Learning System can enhance students’ enthusiasm for knowledge exploration and effectively improve teaching quality. Starting from the perspective of the “basic-clinical” connection teaching in the biochemistry course, this paper analyzes the application value of the AI Case-Guided Learning System and proposes specific application strategies, aiming to accumulate experience for the innovation of biochemistry teaching.</abstract><keywords/></article-meta></front><body/><back><ref-list><ref id="B1" content-type="article"><label>1</label><element-citation publication-type="journal"><p>Wang H, Li D, Wang L, et al., 2025, Reform of Biochemistry Experiment Teaching Oriented by Clinical Practical Ability Cultivation. 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