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<article xsi:noNamespaceSchemaLocation="http://jats.nlm.nih.gov/publishing/1.1/xsd/JATS-journalpublishing1-mathml3.xsd" dtd-version="1.1" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"><front><journal-meta><journal-id journal-id-type="publisher-id">OTD</journal-id><journal-title-group><journal-title>Oncology Treatment Discovery</journal-title></journal-title-group><issn>3083-4996</issn><eissn>2981-8079</eissn><publisher><publisher-name>Bio-Byword Scientific Publishing Pty. Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.26689/otd.v3i4.13452</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title>Effect of Laparoscopic Radical Resection and Open Surgery for Liver Cancer and Their Impact on Inflammatory Factor Levels</title><url>https://artdesignp.com/journal/OTD/3/4/10.26689/otd.v3i4.13452</url><author>ZouJiacheng</author><pub-date pub-type="publication-year"><year>2025</year></pub-date><volume>3</volume><issue>4</issue><history><date date-type="pub"><published-time>2025-12-31</published-time></date></history><abstract>Objective: To evaluate the therapeutic effects of laparoscopic radical resection and open surgery for liver cancer. Methods: A total of 80 liver cancer patients admitted to the hospital from January 2023 to January 2025 were selected and equally divided by a random number table. The observation group underwent laparoscopic radical resection, while the reference group underwent open surgery. Perioperative indicators and inflammatory factor levels were compared between the two groups. Results: The observation group exhibited superior perioperative indicators. One day after surgery, the observation group showed excellent inflammatory factor levels, lower fibrosis factor levels, excellent liver function indicators, and a reduced complication rate, with a statistically significant difference between the groups (P &amp;lt; 0.05). Conclusion: Laparoscopic radical resection for liver cancer is minimally invasive, promotes postoperative recovery, reduces postoperative inflammatory responses, inhibits the progression of liver fibrosis, protects liver function, and demonstrates high surgical safety.</abstract><keywords/></article-meta></front><body/><back><ref-list><ref id="B1" content-type="article"><label>1</label><element-citation publication-type="journal"><p>Liu H, Wang H, Wang X, et al., 2025, The Impact of “Four-Comprehensive” Management Combined with Traditional Chinese Medicine Syndrome Differentiation Nursing on the Psychological State and Quality of Life in Patients Undergoing Laparoscopic Radical Resection for Liver Cancer. International Journal of Nursing, 44(8): 1443–1447.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B2" content-type="article"><label>2</label><element-citation publication-type="journal"><p>Qiu S, Xie H, Wang Y, 2025, Analysis of Influencing Factors for the Occurrence of Hepatic Encephalopathy after Laparoscopic Radical Resection in Patients with Primary Liver Cancer. Practical Journal of Cancer, 40(4): 633–636.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B3" content-type="article"><label>3</label><element-citation publication-type="journal"><p>Medical Administration and Hospital Management Bureau of the National Health and Family Planning Commission of the People’s Republic of China, 2017, Diagnostic and Treatment Specifications for Primary Liver Cancer (2017 Edition). Chinese Journal of Digestive Surgery, 16(7): 13.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B4" content-type="article"><label>4</label><element-citation publication-type="journal"><p>Zhou J, Yu Y, Li T, 2024, High-risk Factors Influencing the Occurrence of Acute Kidney Injury after Laparoscopic Radical Resection in Patients with Primary Liver Cancer. Practical Journal of Cancer, 39(6): 1004–1007.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B5" content-type="article"><label>5</label><element-citation publication-type="journal"><p>Suriguga, 2024, Comparison of the Effects of Laparoscopic Radical Resection and Open Surgery for Liver Cancer. Smart Healthcare, 10(20): 60–62.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B6" content-type="article"><label>6</label><element-citation publication-type="journal"><p>Zhao Y, Peng H, Zhang G, 2024, Effects of Quadratus Lumborum Block on Inflammatory Factors, Pain Mediators, and Cerebral Protection after Laparoscopic Radical Resection of Liver Cancer. Henan Medical Research, 33(7): 1257–1261.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B7" content-type="article"><label>7</label><element-citation publication-type="journal"><p>Wang Y, 2023, Comparison of the Effects of Laparoscopic Radical Resection of Liver Cancer and Open Surgery in the Treatment of Liver Cancer. Chinese Journal of Practical Medicine, 50(11): 12–15.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B8" content-type="article"><label>8</label><element-citation publication-type="journal"><p>Zhang W, 2023, The Effect of Laparoscopic Radical Resection of Liver Cancer on Primary Liver Cancer and Its Impact on the Levels of Inflammatory Factors and Liver Fibrosis-related Factors. Contemporary Medical Symposium, 21(11): 39–41.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B9" content-type="article"><label>9</label><element-citation publication-type="journal"><p>Zhang K, 2025, Comparison of Short-term Efficacy and Prognosis between Laparoscopic Radical Resection of Liver Cancer and Open Surgery in the Treatment of Liver Cancer. Chinese Journal of Practical Rural Doctors, 32(10): 69–72.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B10" content-type="article"><label>10</label><element-citation publication-type="journal"><p>Zhou X, Zhang D, Huang C, 2021, The Effect of Laparoscopic Radical Resection of Liver Cancer Combined with Fuzheng Jiedu Therapy on Primary Liver Cancer and Its Impact on Tumor Markers. Chinese Journal of Integrative Surgery, 27(5): 707–711.</p><pub-id pub-id-type="doi"/></element-citation></ref></ref-list></back></article>
