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<article xsi:noNamespaceSchemaLocation="http://jats.nlm.nih.gov/publishing/1.1/xsd/JATS-journalpublishing1-mathml3.xsd" dtd-version="1.1" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"><front><journal-meta><journal-id journal-id-type="publisher-id">PAR</journal-id><journal-title-group><journal-title>Proceedings of Anticancer Research</journal-title></journal-title-group><issn>2208-3545</issn><eissn>2208-3553</eissn><publisher><publisher-name>Bio-Byword Scientific Publishing Pty. Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.26689/par.v10i1.13742</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title>The Impact of Double-puncture Tympanic Membrane Puncture and Tympanic Cavity Drug Injection on the Complication Rate of Acute Secretory Otitis Media</title><url>https://artdesignp.com/journal/PAR/10/1/10.26689/par.v10i1.13742</url><author>ZhengWei</author><pub-date pub-type="publication-year"><year>2026</year></pub-date><volume>10</volume><issue>1</issue><history><date date-type="pub"><published-time>2026-02-06</published-time></date></history><abstract>Objective: To explore the therapeutic effect of double-puncture tympanic membrane puncture and tympanic cavity drug injection in patients with acute secretory otitis media. Methods: A total of 84 patients with acute secretory otitis media admitted to our hospital from June 2024 to June 2025 were selected and randomly divided into two groups by drawing lots. The control group (42 cases) was treated with the traditional single-puncture tympanic membrane puncture and tympanic cavity drug injection method, while the observation group (42 cases) was treated with the double-puncture tympanic membrane puncture and tympanic cavity drug injection method. The therapeutic effects of the two groups were compared. Results: The overall treatment response rate, overall complication rate, time to symptom relief, and improvement in hearing threshold in the observation group were all superior to those in the control group, with statistically significant differences (P &amp;lt; 0.05). Conclusion: For acute secretory otitis media, the treatment method of double-puncture tympanic membrane puncture and tympanic cavity drug injection demonstrates definite efficacy, significantly reducing the incidence of complications, accelerating symptom relief, and improving hearing function, making it worthy of promotion.</abstract><keywords/></article-meta></front><body/><back><ref-list><ref id="B1" content-type="article"><label>1</label><element-citation publication-type="journal"><p>Xue J, Wang Y, 2024, Analysis of the Therapeutic Effect and Complication Rate of Double-Hole Tympanic Membrane Puncture and Tympanic Cavity Drug Injection for Acute Secretory Otitis Media. Chinese Medical Digest (Otorhinolaryngology), 39(1): 73–76.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B2" content-type="article"><label>2</label><element-citation publication-type="journal"><p>Zhou Y, Wang Z, Yang Z, et al., 2023, Surgical Treatment Options and Efficacy Analysis for Patients with Acute Upper Respiratory Tract Infection Complicated by Secretory Otitis Media. Ningxia Medical Journal, 45(12): 1130–1133.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B3" content-type="article"><label>3</label><element-citation publication-type="journal"><p>Li L, Zhang M, Zhuang W, 2023, Retrospective Analysis of Tympanic Membrane Tube Insertion Combined with Eustachian Tube Balloon Dilation for the Treatment of Adult Refractory Secretory Otitis Media. Chinese Journal of Otorhinolaryngology Integrated Traditional Chinese and Western Medicine, 31(5): 334–337.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B4" content-type="article"><label>4</label><element-citation publication-type="journal"><p>Zhang D, Zheng X, You L, et al., 2023, Clinical Analysis and Efficacy of Ear Endoscopic Tympanic Membrane Incision and Drug Injection Combined with Adenoidectomy for the Treatment of Secretory Otitis Media. Northern Pharmacy, 20(8): 74–76.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B5" content-type="article"><label>5</label><element-citation publication-type="journal"><p>Liu H, Xu Z, 2023, Study on the Efficacy and Safety of Double-Hole Tympanic Membrane Puncture and Tympanic Cavity Drug Injection for Acute Secretory Otitis Media. Chinese Medical Digest (Otorhinolaryngology), 38(1): 77–79 + 86.</p><pub-id pub-id-type="doi"/></element-citation></ref></ref-list></back></article>
