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<article xsi:noNamespaceSchemaLocation="http://jats.nlm.nih.gov/publishing/1.1/xsd/JATS-journalpublishing1-mathml3.xsd" dtd-version="1.1" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"><front><journal-meta><journal-id journal-id-type="publisher-id">PAR</journal-id><journal-title-group><journal-title>Proceedings of Anticancer Research</journal-title></journal-title-group><issn>2208-3545</issn><eissn>2208-3553</eissn><publisher><publisher-name>Bio-Byword Scientific Publishing Pty. Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.26689/par.v10i2.14342</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title>Research on the Determination of Active Ingredient Content in Compound Preparations by High-Performance Liquid Chromatography</title><url>https://artdesignp.com/journal/PAR/10/2/10.26689/par.v10i2.14342</url><author>HeXintong</author><pub-date pub-type="publication-year"><year>2026</year></pub-date><volume>10</volume><issue>2</issue><history><date date-type="pub"><published-time>2026-04-01</published-time></date></history><abstract>Compound preparations are characterized by the synergistic enhancement of multiple components, and their quality control directly affects the safety of medication and the stability of therapeutic efficacy. Due to the complex composition of compound preparations and significant differences in the physicochemical properties of various active ingredients, the detection of their content faces technical challenges, such as difficulties in separation and numerous interfering factors. High-performance liquid chromatography (HPLC), with its advantages of high efficiency, high selectivity, and high sensitivity, has become a core method for quality control of compound preparations, providing reliable data support for evaluating the stability and batch consistency of preparations. Currently, there is an increasing variety of traditional Chinese medicine compound preparations. Establishing a specific, stable, and easy-to-operate method for content determination is of great practical significance for improving the quality standards of traditional Chinese medicine and safeguarding the health of the people.</abstract><keywords/></article-meta></front><body/><back><ref-list><ref id="B1" content-type="article"><label>1</label><element-citation publication-type="journal"><p>Xie H, Ming H, Zhang W, et al., 2026, Determination of Seven Active Ingredients in Hair-Stabilizing Lotion by Dispersed Liquid-Liquid Microextraction-High-Performance Liquid Chromatography. China Pharmaceuticals, 35(5): 100–104.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B2" content-type="article"><label>2</label><element-citation publication-type="journal"><p>Hu H, Bi H, Wang T, et al., 2026, Simultaneous Determination of Seven Components in Fukangbao Oral Liquid by High-Performance Liquid Chromatography. 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