PARProceedings of Anticancer Research2208-35452208-3553Bio-Byword Scientific Publishing Pty. Ltd.10.26689/par.v1i1.3Articlehttps://artdesignp.com/journal/PAR/1/1/10.26689/par.v1i1.3LiuJiajia2020112020-12-31Objective: To evaluate the clinical application of psychotherapy in the nursing center of patients with esophageal cancer. Methods: 100 patients with esophageal cancer treated in our hospital from January 2016 to January 2017 were randomly divided into observation group and control group. Fifty patients in each group were treated with routine rehabilitation. On treatment wise, observation group to take psychological treatment, compared between the two groups before and after treatment of anxiety, depression score, quality of life and CD3 + , CD4 + , CD8 + and other indicators. Results: The scores of depression and anxiety in the observation group were significantly lower than those in the control group (P < 0.05). The CD3 + , CD4 + and CD8 + were significantly higher in the two groups after treatment in compare with before treatment, the difference was statistically significant (P<0.05). Conclusion: Through psychological treatment, it can effectively improve the situation of patients with esophageal cancer, so that the quality of life of patients has been significantly improved, with high efficiency.