PARProceedings of Anticancer Research2208-35452208-3553Bio-Byword Scientific Publishing Pty. Ltd.10.26689/par.v1i2.24Articlehttps://artdesignp.com/journal/PAR/1/2/10.26689/par.v1i2.24LiJiaxin2020122020-12-31Purpose: Analyzing the nursing methods of patients with advanced tumor. Method: Choose 108 patients with advanced tumor from the patients of the hospital. according to the nursing 109 methods, each 54 patients are brought into the control group and the observation group respectively, which are given general nursing and hospic comprehensive nursing intervention measures, and use Self-rating depression scale (SDS) and Self-Rating Anxiety Scale (SAS) to evaluate the psychological situations of the two groups before and after nursing, and to compare the life quality situations and nursing satisfaction rate of the two group patients after nursing. Results: there is no significant difference in psychological status between the two groups before nursing (P > 0.05), but after nursing, the scores of SAS and SDS in the observation group were lower than those in the control group, and the difference is significant (P<0.05), which is statistically significant. For the scores of the life quality, the observation group is higher than that of the control group, the difference is significant (P < 0.05), which is statistically significant. The nursing satisfaction rate of the observation group is 96.30% (52/54), higher than that of the control group (74.07% (40/54)), and the difference is significant (P < 0.05), which is statistically significant. Conclusion: the comprehensive clinical nursing intervention method applying in nursing of patients with advanced tumors plays an important role to improve the psychological status of patients and enhance the life quality of patients and nursing satisfaction rate, which should be widely popularized in nursing practice.