PARProceedings of Anticancer Research2208-35452208-3553Bio-Byword Scientific Publishing Pty. Ltd.10.26689/par.v2i5.709ArticleTherapeutic value of trastuzumab combined with chemotherapy in patients with Her2-positive locally advanced breast cancerhttps://artdesignp.com/journal/PAR/2/5/10.26689/par.v2i5.709HouPengfen2018252018-10-01Abstract: Objective: To evaluate the clinical value of trastuzumab and chemotherapy in patients with Her2-positive locally advanced breast cancer. Methods: Fifty patients with Her2-positive locally advanced breast cancer admitted to our hospital from March 2017 to March 2018 were randomly selected and divided into control group (conventional chemotherapy) and observation group (conventional chemotherapy + trastuzumab). Results: The total effective rate of the observation group was significantly higher than that of the control group, P < 0.05. There was no significant difference in the incidence of adverse reactions between these two groups. Conclusion: The application of trastuzumab combined with chemotherapy in treating Her2-positive locally advanced breast cancer patients can effectively improve its clinical efficacy and has good safety which is worthy of promotion in clinical applications.

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