PARProceedings of Anticancer Research2208-35452208-3553Bio-Byword Scientific Publishing Pty. Ltd.10.26689/par.v8i1.5858ArticleAssessing the Impact of General Anesthesia and Bronchial Intubation in Conjunction with Thoracic Paravertebral Nerve Block on Cellular Immunity and Surgical Management in Tuberculous Pyothorax Patientshttps://artdesignp.com/journal/PAR/8/1/10.26689/par.v8i1.5858DuanChunyu,WangGang,WangBei,XuMan,GaoLijuan2024812024-01-26Objective: This study aims to investigate the impact of combining general anesthesia with bronchial intubation and thoracic paravertebral nerve block during surgery for patients with tuberculous pyothorax. Methods: Eighty patients diagnosed with tuberculous pyothorax, admitted to the hospital between January 2023 and September 2023, were randomly selected for this study. The patients were divided into control and study groups using a numerical table method. The control group underwent general anesthesia with bronchial intubation, while the study group received general anesthesia with bronchial intubation in conjunction with thoracic paravertebral nerve block. Subsequently, the patients were monitored to assess mean arterial pressure, heart rate variations, and adverse reactions to anesthesia. Results: The study group exhibited significantly lower mean arterial pressure and heart rate levels during the post-surgical incision, immediate end of surgery, and immediate extubation periods compared to the control group (P < 0.05). Furthermore, the Ricker and Ramsay scores in the study group were significantly lower than those in the control group (P < 0.05). Conclusion: The combined use of general anesthesia via bronchial intubation and thoracic paravertebral nerve block has been found to stabilize mean arterial pressure and heart rate while providing effective sedation for surgical treatment in patients with tuberculous septic thorax.

Duan C, Liu Z, Liu Y, et al., 2022, Effects of Different Anesthetic Depths on Stress Response and Quality of Resuscitation in Patients Undergoing Tuberculous Septic Thorax Surgery. Clinical Medicine Research and Practice, 7(28): 41–44.

Jiang C, Xiao H, Xu M, et al., 2022, Effects of Perioperative Indexes, Cardiopulmonary Function and Complications in Patients with Tuberculous Pyothorax Treated with Television Thoracoscopy-Assisted Pleural Fiber Plate Debridement. Journal of Practical Hospital Clinics, 19(5): 150–153.

Wu H, 2022, Application Effect of Thoracic Paravertebral Nerve Block Combined with Double-Lumen Bronchial Intubation General Anesthesia in Patients Undergoing Thoracoscopic Pulmonary Herpetic Resection. Zhongguo Nankang Med, 34(4): 14–17.

Xu Y, Xu G, 2022, Clinical Effect of Thoracic Paravertebral Nerve Block on Patients Undergoing Tuberculous Septic Thorax Surgery Under Endobronchial General Anesthesia and Its Influence on Vital Signs Related Indexes, Postoperative Awakening Quality, and Adverse Reactions. Shanxi Medical Journal, 51(1): 50–53.

Chen W, Fang Y, Li G, et al., 2022, Application Effect of Ultrasound-Guided Thoracic Paravertebral Nerve Block Combined with General Anesthesia in Thoracoscopic Surgery of Patients with Tuberculous Pyothorax. Guangxi Medicine, 44(1): 19–22.

Li J, Chen W, Zhang L, 2021, Effects of Ultrasound-Guided Thoracic Paravertebral Nerve Block Combined with General Anesthesia on Stress Indicators and Adverse Reactions in Patients with Tuberculous Pyothorax. Clinical Research, 29(10): 81–82.

Gao Y, Zhao C, 2020, Effects of Propofol and Sevoflurane on Early Postoperative Respiratory Function in Patients with Tuberculous Pyothorax. China Prescription Drugs, 18(9): 192–193.

Ren A, Duan LM, Zhang Y, et al., 2019, Analysis of the Efficacy of Surgical Treatment of Patients with Tuberculous Pyothorax Complicating Quiescent Cirrhosis. Chinese Journal of Anti-Tuberculosis, 41(8): 843–847.

Dong B, 2018, Analysis of the Effect of Sufentanil Compounded with Dizocin on the Treatment of Tuberculous Pyothorax Patients with Self-Controlled Analgesia after Open-Heart Surgery. Psychological Monthly, 2018(11): 74.

Yang Z, 2018, Surgical Efficacy of Different Surgical Styles for Tuberculous Pyothorax and the Effect on Eosinophil Count in Pleural Fluid. Sichuan Journal of Anatomy, 26(3): 138–140.

Hu W, Yuan S, Zhu J, et al., 2017, Feasibility Analysis of Single-Operation Hole Thoracoscopic Pleural Fiber Plate Debridement for Chronic Tuberculous Pyothorax. Chinese Journal of Endoscopy, 23(4): 91–94.

Wan H, Zhao Z, Chen H, et al., 2016, Pharmacokinetic Study of Isoproterenol for General Anesthesia in Patients with Tuberculous Pyothorax. Chinese Clinical Pharmacology and Therapeutics, 21(5): 548–552.

Yao Q, Zhang L, Li Q, 2014, Observation of Sufentanil Compounded with Flurbiprofenate for Postoperative Analgesia after Open-Heart Surgery in Patients with Tuberculous Pyothorax. Modern Medicine and Health, 30(20): 3124–3126.

Zhu C, 2014, Clinical Observation on Surgical Treatment of Chronic Tuberculous Pyothorax. China Medical Guide, 12(14): 74–75.

Liu W, Xu J, Wei M, et al., 2009, Thirty-Seven Cases of Tuberculous Pyothorax Treated by Television Thoracoscopy Under Local Anesthesia. China Medical Frontier, 4(9): 65–66.