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<article xsi:noNamespaceSchemaLocation="http://jats.nlm.nih.gov/publishing/1.1/xsd/JATS-journalpublishing1-mathml3.xsd" dtd-version="1.1" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"><front><journal-meta><journal-id journal-id-type="publisher-id">PAR</journal-id><journal-title-group><journal-title>Proceedings of Anticancer Research</journal-title></journal-title-group><issn>2208-3545</issn><eissn>2208-3553</eissn><publisher><publisher-name>Bio-Byword Scientific Publishing Pty. Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.26689/par.v8i2.6564</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title>A Study on the Influences of the COVID-19 Pandemic-Related Depression, Anxiety, Stress, and Treatment-Crisis on Quality of Life in Cancer Patients – A Secondary Publication</title><url>https://artdesignp.com/journal/PAR/8/2/10.26689/par.v8i2.6564</url><author>KimSo Hyoung,LimKyung Hee</author><pub-date pub-type="publication-year"><year>2024</year></pub-date><volume>8</volume><issue>2</issue><history><date date-type="pub"><published-time>2024-03-28</published-time></date></history><abstract>Objective: To investigate the factors affecting the quality of life of cancer patients by examining the degree of the COVID-19 pandemic-related depression, anxiety, stress, and treatment crisis. Methods: Data were collected from 132 cancer patients undergoing surgery, chemotherapy, radiotherapy, and hormone therapy at K University Hospital in D City using a structured questionnaire. The period of data collection was from May 6 to May 28, 2022. The collected data were analyzed using descriptive statistics, t-test, ANOVA, Pearson’s correlation, and stepwise multiple regression. Results: The mean scores of quality-of-life, depression, anxiety, stress, and treatment crisis during the COVID-19 pandemic were 84.64 ± 29.09, 15.14 ± 6.49, 4.66 ± 5.27, 75.83 ± 17.70, and 78.52 ± 19.95, respectively. In terms of factors affecting the quality of life related to the COVID-19 pandemic, COVID-19 pandemic-related stress (β = 0.41, P &amp;lt; 0.001) appeared to have the greatest impact, followed by COVID-19 pandemic-related treatment-crisis (β = 0.28, P = 0.002), anxiety (β = 0.21, P = 0.002), and gender (β = 0.14, P = 0.009), with a total explanatory power of 67.6%. 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