PARProceedings of Anticancer Research2208-35452208-3553Bio-Byword Scientific Publishing Pty. Ltd.10.26689/par.v9i1.9454ArticleEffectiveness of High-Frequency Electrosurgical Knife Surgery Under Painless Digestive Endoscopy in Elderly Patients with Gastrointestinal Polypshttps://artdesignp.com/journal/PAR/9/1/10.26689/par.v9i1.9454LuYumin2025912025-02-13Objective: To analyze the therapeutic effect of high-frequency electrosurgical knife surgery guided by painless digestive endoscopy (PDE) in elderly patients with gastrointestinal polyps (GP). Methods: A total of 100 elderly GP patients admitted between June 2021 and December 2022 were selected. Patients were randomly divided into two groups: the painless group (50 cases) underwent high-frequency electrosurgical knife surgery guided by PDE, while the conventional group (50 cases) underwent the same surgery guided by traditional digestive endoscopy (DE). The total treatment efficacy, perioperative indicators, gastrointestinal hormone levels, oxidative stress (OS) markers, and complication rates were compared between the two groups. Results: The total treatment efficacy in the painless group was higher than that in the conventional group, and perioperative indicators were superior in the painless group (P < 0.05). One week after treatment, the gastrointestinal hormone levels and OS-related markers in the painless group were better than those in the conventional group (P < 0.05). The complication rate in the painless group was lower than in the conventional group (P < 0.05). Conclusion: High-frequency electrosurgical knife surgery guided by PDE improves the effectiveness of polyp removal in elderly GP patients and accelerates postoperative recovery. It also protects gastrointestinal function, reduces postoperative OS, and ensures higher surgical safety.

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