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<article xsi:noNamespaceSchemaLocation="http://jats.nlm.nih.gov/publishing/1.1/xsd/JATS-journalpublishing1-mathml3.xsd" dtd-version="1.1" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"><front><journal-meta><journal-id journal-id-type="publisher-id">PAR</journal-id><journal-title-group><journal-title>Proceedings of Anticancer Research</journal-title></journal-title-group><issn>2208-3545</issn><eissn>2208-3553</eissn><publisher><publisher-name>Bio-Byword Scientific Publishing Pty. Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.26689/par.v9i6.12908</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title>Meta-Synthesis of Physical and Psychological Experiences During PICC Maintenance in Cancer Patients Undergoing Chemotherapy</title><url>https://artdesignp.com/journal/PAR/9/6/10.26689/par.v9i6.12908</url><author>ZhengXueyun,AnYanping,TuXulian</author><pub-date pub-type="publication-year"><year>2025</year></pub-date><volume>9</volume><issue>6</issue><history><date date-type="pub"><published-time>2025-12-08</published-time></date></history><abstract>Objective: To explore the real experience of the maintenance of patients with a central venous catheter (PICC) inserted by peripheral venipentesis, and to provide a reference for improving the quality of life of patients with cancer chemotherapy with catheter indentation and regular maintenance. Methods:&amp;nbsp; Qualitative studies on the real experience of patients with PICC catheterization were searched from domestic and foreign databases from the establishment of the database to November 31, 2024, and the meta-integration method was used to integrate and summarize the study results. Results: A total of 10 studies were included, 63 topics were extracted, 9 categories were summarized, and 3 results were integrated. PICC-induced life behavior change, skin stress reaction and economic cost consideration (life disturbance caused by PICC, unpleasant experience caused by film, economic pressure), from patient to nursing: Chain reaction factors of PICC maintenance risk (lax patient self-management, nurses worried about overprotective family members, nursing professional deficiencies, and education gaps): The maintenance and integration results of 3 PICC catheters: the trigger of PICC maintenance risk, multi-factor psychological stress, family nurse support and education difficulties analysis (psychological stress under PICC multi-factor and role transformation during the treatment interval, PICC maintenance experience, family support. Conclusion: During the use of PICC (Peripherally Inserted Central Catheter) for tumor chemotherapy patients, they are faced with issues such as the curling of the dressing. In order to enhance the patients’ treatment effectiveness and quality of life, comprehensive considerations are required. By strengthening the training of nurses, optimizing health education, improving the awareness and compliance of patients and their families, enhancing the maintenance experience, and reducing the economic burden, we can address the numerous problems that occur during the use of PICC.</abstract><keywords/></article-meta></front><body/><back><ref-list><ref id="B1" content-type="article"><label>1</label><element-citation publication-type="journal"><p>Dong X, Yu T, Cao M, et al., 2023, Meta-Synthesis of Qualitative Research on the Real Experiences of Patients With PICC Catheterization. Evidence-Based Nursing, 9(21): 3836–3842.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B2" content-type="article"><label>2</label><element-citation publication-type="journal"><p>Guo Y, Xue L, Tang W, et al., 2024, Ovarian Microenvironment: Challenges and Opportunities in Protecting Against Chemotherapy-Associated Ovarian Damage. Hum Reprod Update, 30(5): 614–647.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B3" content-type="article"><label>3</label><element-citation publication-type="journal"><p>Sun W, 2022, Construction of a Risk Assessment Model for Peripheral Intravenous Catheter-Related Complications in ICU Patients, thesis, Qingdao University.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B4" content-type="article"><label>4</label><element-citation publication-type="journal"><p>Wu X, Zhou Y, Chen S, et al, 2025, Meta-Synthesis of Factors Impeding Dietary Management in Patients With Gestational Diabetes Mellitus. Journal of Nurses Training, 40(05): 530–539 + 544.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B5" content-type="article"><label>5</label><element-citation publication-type="journal"><p>Zhang Y, Li X, Wu J, et al., 2024, Interpretation of the Evidence Summary Production Process at the JBI Evidence-Based Health Care Center. Journal of Nursing, 31(16): 39–43.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B6" content-type="article"><label>6</label><element-citation publication-type="journal"><p>Yang Q, Lu Q, Ou M, et al., 2020, Qualitative Research on the Longitudinal Experience of Cancer Patients With PICC Catheters. Contemporary Nurse (First Issue), 27(08): 9–12.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B7" content-type="article"><label>7</label><element-citation publication-type="journal"><p>Zhang M, Gao W, Sun Y, et al., 2014, Substantive Research on the Real Experiences of Cancer Patients During the Indwelling Period of Peripherally Inserted Central Catheters. Chinese Journal of Nursing, 31(19): 1–5.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B8" content-type="article"><label>8</label><element-citation publication-type="journal"><p>Duan J, Jiang W, Cai Y, et al., 2018, Qualitative Research on the Real Experiences of Gynecological Cancer Patients With PICC Catheters at Different Stages. Journal of Integrative Nursing (Chinese and English), 4(07): 76–79.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B9" content-type="article"><label>9</label><element-citation publication-type="journal"><p>Shang L, Dong H, Xu X, et al., 2014, Qualitative Research on the Self-Management Experiences of Patients With PICC Catheters During Chemotherapy Intervals. Nursing Research, 28(01): 48–50.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B10" content-type="article"><label>10</label><element-citation publication-type="journal"><p>Gao Y, Wang L, 2020, A Qualitative Study on the Real Experience of Breast Cancer Patients Undergoing Chemotherapy With Indwelling PICC. General Practice Nursing, 18(18): 2275–2277.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B11" content-type="article"><label>11</label><element-citation publication-type="journal"><p>Zhu P, Liu J, Meng A, et al., 2016, A Qualitative Study on the Experience of PICC Catheterization in Cancer Patients. Nursing Research, 30(17): 2114–2117.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B12" content-type="article"><label>12</label><element-citation publication-type="journal"><p>Parás-Bravo P, Paz-Zulueta M, Santibañez M, et al., 2018, Living With a Peripherally Inserted Central Catheter: The Perspective of Cancer Outpatients—A Qualitative Study. Support Care Cancer, 26(2): 441–449.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B13" content-type="article"><label>13</label><element-citation publication-type="journal"><p>Li Q, Yan M, Lin C, et al., 2012, A Substantive Study on the Real Experience of Cancer Patients Choosing Indwelling PICC. Journal of Nursing Science, 27(05): 40–42.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B14" content-type="article"><label>14</label><element-citation publication-type="journal"><p>Xu P, Hu H, Shao X, et al., 2017, A Qualitative Study on the Experience of PICC Catheterization in Chemotherapy Patients in the Oncology Department. Qilu Nursing Journal, 23(15): 38–40.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B15" content-type="article"><label>15</label><element-citation publication-type="journal"><p>Li J, Jiang C, Guan S, et al., 2018, A Qualitative Study on the Psychological Experience of Chemotherapy Patients Before and After PICC Catheterization. Medical Information, 31(05): 164–166.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B16" content-type="article"><label>16</label><element-citation publication-type="journal"><p>Chen L, Li J, Yang Y, et al., 2023, Training and Effectiveness of PICC Maintenance for Grassroots Nurses in Guangdong Province. Chinese Journal of Nursing Education, 20(02): 194–199.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B17" content-type="article"><label>17</label><element-citation publication-type="journal"><p>Yang M, Ma F, 2021, A Longitudinal Study on the Transfer Behavior and Its Influencing Factors After Standardized Training in PICC Technology. Journal of Nursing Science, 36(05): 59–61.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B18" content-type="article"><label>18</label><element-citation publication-type="journal"><p>Xiao S, Zhang X, Chen Q, 2019, Application of Staged Telephone Follow-Up Health Education in Breast Cancer Patients Undergoing PICC Catheterization and Chemotherapy. International Medicine &amp; Health Guidance News, 25(24): 1007–1245.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B19" content-type="article"><label>19</label><element-citation publication-type="journal"><p>Li X, Chen K, Zhao J, et al., 2024, Meta-Analysis of the Impact of PICC Placement via Different Upper Limbs on Catheterization Outcomes. Journal of Nursing Administration, 24(10): 887–892.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B20" content-type="article"><label>20</label><element-citation publication-type="journal"><p>Ma G, 2023, Research on Risk Factors and Predictive Models for Unplanned Extubation of PICC in Tumor Patients, thesis, Central South University.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B21" content-type="article"><label>21</label><element-citation publication-type="journal"><p>Böll B, Schalk E, Buchheidt D, et al., 2021, Central Venous Catheter-Related Infections in Hematology and Oncology: 2020 Updated Guidelines on Diagnosis, Management, and Prevention. Ann Hematol, 100(1): 239–259.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B22" content-type="article"><label>22</label><element-citation publication-type="journal"><p>Bing S, Smotherman C, Rodriguez R, et al., 2022, PICC Versus Midlines: Comparison of Peripherally Inserted Central Catheters and Midline Catheters With Respect to Incidence of Thromboembolic and Infectious Complications. Am J Surg, 223(5): 983–987.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B23" content-type="article"><label>23</label><element-citation publication-type="journal"><p>Xiong X, 2023, The Impact of Continuous Nursing Intervention on Patients With Acute Myocardial Infarction After PCI: A Review of “Humanistic Nursing and Communication Skills in the Operating Room”. Chinese Journal of Experimental Traditional Medical Formulae, 29(09): 178.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B24" content-type="article"><label>24</label><element-citation publication-type="journal"><p>Hao M, Mi J, Xu Z, 2025, Analysis of the Application Effect of Continuous Nursing Pathway in Patients With Tuberculous Meningitis. Chinese Journal of Antituberculosis, 1–9.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B25" content-type="article"><label>25</label><element-citation publication-type="journal"><p>Xu L, 2023, Construction and Application of a Risk Early Warning Ability Indicator System for Online-Booked Nurses in Venous Catheter Maintenance Under the “Internet + Nursing Services” Model, thesis, Qingdao University.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B26" content-type="article"><label>26</label><element-citation publication-type="journal"><p>Quan S, Hao F, Lai W, et al, 2023, Research on the Effectiveness of “Internet +” Home-Based Nursing Services for PICC Patients. Journal of Nursing Administration, 23(10): 786–789 + 829.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B27" content-type="article"><label>27</label><element-citation publication-type="journal"><p>Jing T, Wu S, Peng Y, 2022, Application Research of an Integrated Nurse-Physician Risk Management Model in Patients With Acute Leukemia Undergoing Peripherally Inserted Central Catheter (PICC) Placement. Journal of Chengdu Medical College, 17(01): 124–127.</p><pub-id pub-id-type="doi"/></element-citation></ref><ref id="B28" content-type="article"><label>28</label><element-citation publication-type="journal"><p>Liu F, Lv Y, Li D, et al., 2021, The Impact of Self-Care Ability Education and Guidance Based on a WeChat Management Platform on Patients With Stomas in Gastrointestinal Surgery. Chinese Journal of Modern Nursing, 27(26): 3613–3617.</p><pub-id pub-id-type="doi"/></element-citation></ref></ref-list></back></article>
