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<article xsi:noNamespaceSchemaLocation="http://jats.nlm.nih.gov/publishing/1.1/xsd/JATS-journalpublishing1-mathml3.xsd" dtd-version="1.1" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"><front><journal-meta><journal-id journal-id-type="publisher-id">SSR</journal-id><journal-title-group><journal-title>Scientific and Social Research</journal-title></journal-title-group><issn>2661-4332</issn><eissn>2981-9946</eissn><publisher><publisher-name>Bio-Byword Scientific Publishing Pty. Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.26689/ssr.v8i8.15234</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title>Research Progress on Artificial Intelligence-Based Early Diagnosis and Treatment of Alzheimer's Disease</title><url>https://artdesignp.com/journal/SSR/8/8/10.26689/ssr.v8i8.15234</url><author>ShaRoujia,FengWeike</author><pub-date pub-type="publication-year"><year>2026</year></pub-date><volume>8</volume><issue>8</issue><history><date date-type="pub"><published-time>2026-08-31</published-time></date></history><abstract>Alzheimer&amp;rsquo;s disease (AD) is one of the most common neurodegenerative diseases and continues to place a considerable burden on public health systems worldwide. Owing to its complicated pathological mechanisms, difficulties associated with early diagnosis, and the lack of treatments capable of halting disease progression, AD remains a major focus of current research. In recent years, artificial intelligence (AI) has increasingly been introduced into this field. Methods based on machine learning, deep learning, and the integration of different types of data have shown potential in several aspects of AD research and clinical care. Existing studies have explored the use of AI for identifying AD at earlier stages, analyzing neuroimaging data, estimating disease progression, supporting digital health interventions, and assisting drug development. This review summarizes recent work in these areas and focuses on several topics that have attracted particular attention, such as neuroimaging applications, biomarker discovery, cognitive and behavioral evaluation, long-term disease monitoring, and therapeutic support. At the same time, a number of issues continue to limit wider clinical adoption. Differences in data sources, insufficient generalizability of some models, and concerns regarding ethics, privacy, and data security are among the challenges most frequently discussed in the literature. Addressing these problems will be important for the future development and practical use of AI-based approaches in AD diagnosis and management.</abstract><keywords>Alzheimer’s disease, Artificial intelligence, Machine learning, Deep learning, Neuroimaging, Blood biomarkers</keywords></article-meta></front><body/><back><ref-list><ref id="B1" content-type="article"><label>1</label><element-citation publication-type="journal"><p>[1] Jack CR, Bennett AD, Blennow K, et al., 2018, NIA-AA Research Framework: Toward a Biological Definition of Alzheimer&amp;rsquo;s Disease. Alzheimer&amp;rsquo;s &amp;amp; Dementia: The Journal of the Alzheimer&amp;rsquo;s Association, 14(4): 535&amp;ndash;562. https://doi.org/10.1016/j.jalz.2018.02.018
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